Gut microbiota includes a vast collection of microorganisms residing within the
gastrointestinal tract. It is broadly recognized that the gut and brain are in constant …

Due to the increasing prevalence of life-threatening bacterial, fungal and viral infections and
the ability of these human pathogens to develop resistance to current treatment strategies …

Bacterial specialized metabolites are a proven source of antibiotics and cancer therapies,
but whether we have sampled all the secondary metabolite chemical diversity of cultivated …

Both nitrogen deposition (ND) and microplastics (MPs) pose global change challenges. The
effects of MPs co-existing with ND on ecosystem functions are still largely unknown. Herein …

Emergence of antibiotic resistant pathogenic bacteria poses a serious public health
challenge worldwide. However, antibiotic resistance genes are not confined to the clinic; …

There is a real consensus that new antibiotics are urgently needed and are the best chance
for combating antibiotic resistance. The phylum Actinobacteria is one of the main producers …

In macroecology, the concept of r‐and K‐strategy has been widely applied, yet, there have
been limited studies on microbial life‐history strategies in temperate grasslands using …

The application of phylogenetic taxonomic procedures led to improvements in the
classification of bacteria assigned to the phylum Actinobacteria but even so there remains a …

Actinobacteria constitute a highly diverse bacterial phylum with an unrivalled metabolic
versatility. They produce most of the clinically used antibiotics and a plethora of other natural …

Bacteria provide a rich source of natural products with potential therapeutic applications,
such as novel antibiotic classes or anticancer drugs. Bioactivity-guided screening of …