The first practice of pre-implantation genetic testing (PGT) was reported more than 30 years
ago. PGT, originally named preimplantation genetic screening (PGS) and pre-implantation …

BACKGROUND The genetic composition of embryos generated by in vitro fertilization (IVF)
can be examined with preimplantation genetic testing (PGT). Until recently, PGT was limited …

Purpose Preimplantation genetic testing for monogenic disorders (PGT-M) allows early
diagnosis in embryos conceived in vitro. PGT-M helps to prevent known genetic disorders in …

Recent advances in genomic technologies expand the scope and efficiency of
preimplantation genetic testing (PGT). We previously developed Haploseek, a clinically …

Preimplantation genetic testing (PGT) has emerged as a powerful companion to assisted
reproduction technologies. The origins and history of PGT are reviewed here, along with …

Purpose The preimplantation genetic testing for aneuploidy (PGT-A) platform is not currently
available for small copy-number variants (CNVs), especially those< 1 Mb. Through …

Preimplantation genetic testing for monogenic diseases (PGT-M) can be used to select
embryos that do not develop disease phenotypes or carry disease-causing genes for …

Research question Is there a precise and efficient haplotyping method to expand the
application on preimplantation genetic testing (PGT)? Design In this study, 8 cell line …

Sequencing technology has undergone major breakthroughs over time and has become
indispensable in biological and medical research. Advances in protocols and analysis …

Single cell copy number variation sequencing (scCNV-seq) is valuable for genomic analysis
of a variety of health and disease systems, yet the available methods either depend on …