Osteoimmunology is at full display during endosseous implant osseointegration. Bone
formation, maintenance and resorption at the implant surface is a result of bidirectional and …

Macrophages are versatile immune cells and can adapt to both external stimuli and their
surrounding environment. Macrophages are categorized into two major categories; M1 …

Energy metabolism plays an important role in cell and tissue ability to effectively function,
maintain homeostasis, and perform repair. Yet, the role of energy metabolism in skeletal …

The discovery of histone demethylases has revealed the dynamic nature of the regulation of
histone methylation. KDM2B is an important histone lysine demethylase that removes methyl …

The availability of large human datasets for genome-wide association studies (GWAS) and
the advancement of sequencing technologies have boosted the identification of genetic …

Periodontal ligament stem cells (PDLCs) can be used as a valuable source in cell therapies
to regenerate bone tissue. However, the potential therapeutic outcomes are unpredictable …

It is widely accepted that sandblasted/large-grit/acid-etched (SLA) surfaces of titanium (Ti)
have a higher osteogenic potential than machined ones. However, most studies focused on …

DNA methylation is an epigenetic modification critical for the regulation of chromatin
structure and gene expression during development and disease. The ten‐eleven …

Abstract Purpose of Review Epigenetic mechanisms modify gene activity in a stable manner
without altering DNA sequence. They participate in the adaptation to the environment, as …

We previously established that DNA methyltransferase 3b (Dnmt3b) is the sole Dnmt
responsive to fracture repair and that Dnmt3b expression is induced in progenitor cells …