Antibiotic-induced collateral damage to the microbiota and associated infections
Antibiotics have transformed medicine, saving millions of lives since they were first used to
treat a bacterial infection. However, antibiotics administered to target a specific pathogen …
treat a bacterial infection. However, antibiotics administered to target a specific pathogen …
Interkingdom interactions between Pseudomonas aeruginosa and Candida albicans affect clinical outcomes and antimicrobial responses
LJ Kahl, N Stremmel, MA Esparza-Mora… - Current Opinion in …, 2023 - Elsevier
Infections that involve interkingdom microbial communities, such as those between bacteria
and yeast pathogens, are difficult to treat, associated with worse patient outcomes, and may …
and yeast pathogens, are difficult to treat, associated with worse patient outcomes, and may …
Ecological and evolutionary mechanisms driving within-patient emergence of antimicrobial resistance
The ecological and evolutionary mechanisms of antimicrobial resistance (AMR) emergence
within patients and how these vary across bacterial infections are poorly understood …
within patients and how these vary across bacterial infections are poorly understood …
One species, many faces: The underappreciated importance of strain diversity
J Nysten, D Sofras, P Van Dijck - PLoS Pathogens, 2024 - journals.plos.org
Over the past century, extensive efforts have been made to isolate and categorize thousands
of strains, resulting in the classification of species as a group of strains that form a coherent …
of strains, resulting in the classification of species as a group of strains that form a coherent …
The microbiota: a crucial mediator in gut homeostasis and colonization resistance
Y Chen, L Xiao, M Zhou, H Zhang - Frontiers in Microbiology, 2024 - frontiersin.org
The gut microbiota is a complex and diverse community of microorganisms that colonizes
the human gastrointestinal tract and influences various aspects of human health. These …
the human gastrointestinal tract and influences various aspects of human health. These …
Antibiotic resistance alters the ability of Pseudomonas aeruginosa to invade bacteria from the respiratory microbiome
S Lindon, S Shah, DR Gifford, C Lood… - Evolution …, 2024 - academic.oup.com
The emergence and spread of antibiotic resistance in bacterial pathogens is a global health
threat. One important unanswered question is how antibiotic resistance influences the ability …
threat. One important unanswered question is how antibiotic resistance influences the ability …
Double-Network Hydrogel with Strengthened Mechanical Property for Controllable Release of Antibacterial Peptide
T Tan, Y Hou, Y Zhang, B Wang - Biomacromolecules, 2024 - ACS Publications
Developing double-network (DN) hydrogels with high mechanical properties and
antibacterial efficacy to combat multidrug-resistant bacterial infections and serve as scaffolds …
antibacterial efficacy to combat multidrug-resistant bacterial infections and serve as scaffolds …
Epidemiology of healthcare-associated Pseudomonas aeruginosa in intensive care units: are sink drains to blame?
C Volling, L Mataseje, L Graña-Miraglia, X Hu… - Journal of Hospital …, 2024 - Elsevier
Background Pseudomonas aeruginosa (PA) is a common cause of healthcare-associated
infection (PA-HAI) in the intensive care unit (ICU). Aim To describe the epidemiology of PA …
infection (PA-HAI) in the intensive care unit (ICU). Aim To describe the epidemiology of PA …
The role of hypermutation and collateral sensitivity in antimicrobial resistance diversity of Pseudomonas aeruginosa populations in cystic fibrosis lung infection
Pseudomonas aeruginosa is an opportunistic pathogen which causes chronic, drug-
resistant lung infections in cystic fibrosis (CF) patients. In this study, we explore the role of …
resistant lung infections in cystic fibrosis (CF) patients. In this study, we explore the role of …
Demographic fluctuations in bloodstream Staphylococcus aureus lineages configure the mobile gene pool and antimicrobial resistance
Staphylococcus aureus in the bloodstream causes high morbidity and mortality, exacerbated
by the spread of multidrug-resistant and methicillin-resistant S. aureus (MRSA). We aimed to …
by the spread of multidrug-resistant and methicillin-resistant S. aureus (MRSA). We aimed to …