More than 95 percent of infants who have neonatal stroke survive to adulthood, and many
have residual motor or cognitive disabilities. This article makes the point that recognition of …

Past the age of 50 years, aging individuals lose muscle mass at an approximate rate of 1–
2% per year. This age-related muscle atrophy, termed sarcopenia, can have significant …

Periventricular leukomalacia (PVL), the major substrate of cerebral palsy in survivors of
prematurity, is defined as focal periventricular necrosis and diffuse gliosis in immature …

AGING AND NEURODEGENERATION: MOLECULAR AND CELLULAR BASES Summary.
Objective. A review about the possible cellular and molecular mechanisms of aging and …

Nitric oxide (NO) reacts with superoxide anion to form the peroxynitrite anion (ONOO−), a
molecule with pulmonary vasodilator properties in the adult rat. The purpose of this study …

Neonatal encephalopathy is a common central nervous system disorder of neonatal foals
and human infants, resulting in clinical signs such as lethargy, inappropriate behavior …

Abstract 'Permissive hypercapnia'is a familiar term in neonatal intensive care, given the
widespread adoption of low‐tidal‐volume ventilation strategies applied with the goal of …

Background Newborn resuscitation with 100% oxygen is associated with oxidative-nitrative
stresses and inflammation. The mechanisms are unclear. Hyaluronan (HA) is fragmented to …

Hypothesis: Nitrotyrosine, a reaction product of peroxynitrite and proteins, could be
demonstrated in the postmortem examination of brain tissue of full-term neonates who had …

Inflammation participates in the genesis and progression of hypoxic-ischemic brain injury.
Interleukin (IL)-1 is a major pro-inflammatory cytokine, which plays a dominant role in …