Amyotrophic lateral sclerosis: new perpectives and update
M Orsini, AB Oliveira, OJM Nascimento… - Neurology …, 2015 - mdpi.com
Amyotrophic lateral sclerosis (ALS), Charcot's disease or Lou Gehrig's disease, is a term
used to cover the spetrum of syndromes caracterized by progressive degeneration of motor …
used to cover the spetrum of syndromes caracterized by progressive degeneration of motor …
Pharmacogenomics of Alzheimer's disease: Novel therapeutic strategies for drug development
R Cacabelos, P Cacabelos, C Torrellas… - … in Drug Discovery and …, 2014 - Springer
Alzheimer's disease (AD) is a major problem of health and disability, with a relevant
economic impact on our society. Despite important advances in pathogenesis, diagnosis …
economic impact on our society. Despite important advances in pathogenesis, diagnosis …
Therapeutic progress in amyotrophic lateral sclerosis-beginning to learning
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with
motor neuron degeneration, muscle weakness, paralysis and finally death. The proposed …
motor neuron degeneration, muscle weakness, paralysis and finally death. The proposed …
In silico exploration of metabolically active peptides as potential therapeutic agents against amyotrophic lateral sclerosis
TH Fatoki, S Chukwuejim, CC Udenigwe… - International Journal of …, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is regarded as a fatal neurodegenerative disease that is
featured by progressive damage of the upper and lower motor neurons. To date, over 45 …
featured by progressive damage of the upper and lower motor neurons. To date, over 45 …
Advances in nanomedicine for the treatment of Alzheimer's and Parkinson's diseases
S Hernando, O Gartziandia, E Herran, JL Pedraz… - …, 2016 - Taylor & Francis
Alzheimer's disease and Parkinson's disease are the most common neurodegenerative
diseases worldwide. Despite all the efforts made by the scientific community, current …
diseases worldwide. Despite all the efforts made by the scientific community, current …
Mini-GAGR, an intranasally applied polysaccharide, activates the neuronal Nrf2-mediated antioxidant defense system
K Murphy, K Llewellyn, S Wakser, J Pontasch… - Journal of Biological …, 2018 - ASBMB
Oxidative stress triggers and exacerbates neurodegeneration in Alzheimer's disease (AD).
Various antioxidants reduce oxidative stress, but these agents have little efficacy due to poor …
Various antioxidants reduce oxidative stress, but these agents have little efficacy due to poor …
Novel therapeutic strategies for dementia
R Cacabelos, C Torrellas, I Carrera… - CNS & Neurological …, 2016 - ingentaconnect.com
Dementia represents a major problem of health and disability, with a relevant economic
impact on our society. Despite important advances in pathogenesis, diagnosis and …
impact on our society. Despite important advances in pathogenesis, diagnosis and …
Exploring bioactive peptides as potential therapeutic and biotechnology treasures: A contemporary perspective
In preceding years, bioactive peptides (BAPs) have piqued escalating attention owing to
their multitudinous biological features. To date, many potential BAPs exhibiting anti-cancer …
their multitudinous biological features. To date, many potential BAPs exhibiting anti-cancer …
Potential therapeutic drugs and methods for the treatment of amyotrophic lateral sclerosis
G Yacila, Y Sari - Current medicinal chemistry, 2014 - ingentaconnect.com
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disorder caused by damage of
motoneurons leading to paralysis state and long term disability. Riluzole is currently the only …
motoneurons leading to paralysis state and long term disability. Riluzole is currently the only …
Safety and feasibility of lin-cells administration to ALS patients: a novel view on humoral factors and miRNA profiles
A Sobuś, B Baumert, Z Litwińska… - International journal of …, 2018 - mdpi.com
Therapeutic options for amyotrophic lateral sclerosis (ALS) are still limited. Great hopes,
however, are placed in growth factors that show neuroprotective abilities (eg, nerve growth …
however, are placed in growth factors that show neuroprotective abilities (eg, nerve growth …