Hypertension and type 2 diabetes—the novel treatment possibilities

A Przezak, W Bielka, A Pawlik - International Journal of Molecular …, 2022 - mdpi.com
Elevated blood pressure and hyperglycaemia frequently coexist and are both components of
metabolic syndrome. Enhanced cardiovascular risk is strongly associated with diabetes and …

Diabetes leading to heart failure and heart failure leading to diabetes: epidemiological and clinical evidence

A Palazzuoli, M Iacoviello - Heart Failure Reviews, 2023 - Springer
Type 2 diabetes mellitus (T2DM) is a risk factor that plays a major role in the onset of heart
failure (HF) both directly, by impairing cardiac function, and indirectly, through associated …

Obesity, metabolic syndrome, and primary hypertension

M Litwin, Z Kułaga - Pediatric Nephrology, 2021 - Springer
Primary hypertension is the dominant form of arterial hypertension in adolescents. Disturbed
body composition with, among other things, increased visceral fat deposition, accelerated …

Primary prevention of ASCVD and T2DM in patients at metabolic risk: an Endocrine Society clinical practice guideline

JL Rosenzweig, GL Bakris, LF Berglund… - The Journal of …, 2019 - academic.oup.com
Objective To develop clinical practice guidelines for the primary prevention of atherosclerotic
cardiovascular disease (ASCVD) and type 2 diabetes mellitus (T2DM) in individuals at …

Therapeutic properties of highly selective β-blockers with or without additional vasodilator properties: focus on bisoprolol and nebivolol in patients with cardiovascular …

W AlHabeeb, S Mrabeti, AAI Abdelsalam - Cardiovascular Drugs and …, 2022 - Springer
Bisoprolol and nebivolol are highly selective β1-adrenoceptor antagonists, with clinical
indications in many countries within the management of heart failure with reduced left …

Nebivolol in the treatment of arterial hypertension

N Olawi, M Krüger, D Grimm, M Infanger… - Basic & Clinical …, 2019 - Wiley Online Library
This MiniReview reports the current knowledge about the treatment of arterial hypertension
with the third‐generation beta‐adrenoceptor antagonist (BAA) nebivolol. Furthermore, it …

Developed electrochemical sensors for the determination of beta-blockers: a comprehensive review

MRJ Sarvestani, T Madrakian, A Afkhami - Journal of Electroanalytical …, 2021 - Elsevier
Abstract Beta-blockers (β-blockers) are a special type of medicine that are prescribed for a
wide range of health problems including cardiovascular diseases. There is a narrow border …

Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: an in silico structure-based approach

O Mutlu, OM Ugurel, E Sariyer, O Ata… - Journal of …, 2022 - Taylor & Francis
In this study, the Nsp12–Nsp8 complex of SARS-CoV-2 was targeted with structure-based
and computer-aided drug design approach because of its vital role in viral replication …

Clinical pharmacokinetics of nebivolol: a systematic review

N Hanif, A Zamir, I Imran, H Saeed… - Drug Metabolism …, 2023 - Taylor & Francis
Nebivolol is a beta-1 receptor blocker used to treat hypertension, heart failure, erectile
dysfunction, vascular disease, and diabetes mellitus. This review investigated the data …

[HTML][HTML] Hypertension in diabetes

S Naha, MJ Gardner, D Khangura, LR Kurukulasuriya… - 2015 - europepmc.org
The coexistence of diabetes and hypertension is known to have a multiplicative effect on
adverse clinical outcomes with respect to both microvascular and macrovascular disease …