Design, synthesis fusidic acid derivatives alleviate acute lung injury via inhibiting MAPK/NF-κB/NLRP3 pathway
Z Liu, X Huang, HY Guo, LW Zhang, YS Quan… - European Journal of …, 2023 - Elsevier
Acute lung injury (ALI) refers to a series of lung lesions resulting from multiple lung injuries,
even leading to morbidity and death, abundant previous reports have showed that anti …
even leading to morbidity and death, abundant previous reports have showed that anti …
A comprehensive review on the pharmacological role of gut microbiome in neurodegenerative disorders: potential therapeutic targets
Neurological disorders, including Alzheimer and Parkinson's, pose significant challenges to
public health due to their complex etiologies and limited treatment options. Recent advances …
public health due to their complex etiologies and limited treatment options. Recent advances …
[HTML][HTML] The combination of Tanshinone IIA and Astragaloside IV attenuates myocardial ischemia–reperfusion injury by inhibiting the STING pathway
P Zhai, Q Chen, X Wang, X Ouyang, M Yang, Y Dong… - Chinese Medicine, 2024 - Springer
Abstract Background Astragaloside IV (As-IV) and Tanshinone IIA (Ta-IIA) are the main
ingredients of traditional Chinese medicinal Astragalus membranaceus (Fisch.) Bunge and …
ingredients of traditional Chinese medicinal Astragalus membranaceus (Fisch.) Bunge and …
[HTML][HTML] Tyrosol attenuates NASH features by reprogramming the hepatic immune milieu
D Gabbia, K Sayaf, I Zanotto, M Colognesi… - European Journal of …, 2024 - Elsevier
Nonalcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease, and no
drugs have been approved for its therapy. Among plant-derived molecules, phenolic …
drugs have been approved for its therapy. Among plant-derived molecules, phenolic …
The Immune-Stimulating and Anti-Diabetic Effects of Allium hookeri Leaves Grown in a Plant Factory with Artificial Lights in Immunosuppressed Obese C57BL/6 Mice
J Jung, JS Kim, UY Jeong, UJ Bae, M Kim, SY Park… - Pharmaceuticals, 2024 - mdpi.com
We investigated the immune-stimulating and anti-diabetic effects of Allium hookeri leaves
grown in a plant factory with artificial lights. The immunomodulatory effects of A. hookeri …
grown in a plant factory with artificial lights. The immunomodulatory effects of A. hookeri …
Endogenous blocking of TLR2 along with TNF-α and IL-1β ameliorates the severity of the S. aureus arthritis via modulating STAT3/SOCS3 expressions in tissue …
R Ghosh, B Bishayi - Microbial Pathogenesis, 2024 - Elsevier
In vivo studies identifying a role of TLR2 in septic arthritis models are lacking. TNF-α played
as the most important proinflammatory cytokine, and connected directly to the pathogenesis …
as the most important proinflammatory cytokine, and connected directly to the pathogenesis …
Computational analysis followed by in vitro studies to explore cytokines (TNF‐α, IL‐6 and IL‐1β) inhibition potential of the new natural molecule polonilignan
Targeting pro‐inflammatory cytokines and their production is found to be of therapeutic
benefit for the regulation of inflammation in various chronic autoimmune diseases. Our …
benefit for the regulation of inflammation in various chronic autoimmune diseases. Our …
Molecular networking-guided isolation strategy of a new C-glycosyl flavone rotamer from Stellaria alsine and evaluation of anti-inflammatory and antioxidant …
CK Kim, S Yu, M Lee - Metabolomics, 2023 - Springer
Introduction Stellaria alsine has traditionally been used as both a famine relief food and an
alternative medicine in East Asia. Modern pharmacological studies have revealed that S …
alternative medicine in East Asia. Modern pharmacological studies have revealed that S …
基于多种化疗肠损伤发生机制的中医药防治进展
李爽, 韩淑贞, 戴瑜婷, 修明慧… - 中国临床药理学 …, 2023 - manu41.magtech.com.cn
肠损伤是临床应用化疗药物的常见不良反应, 限制了化疗药的进一步应用, 并给病人造成严重的
身心负担. 目前化疗肠损伤的发生机制比较复杂, 中医药具有极好的防治作用 …
身心负担. 目前化疗肠损伤的发生机制比较复杂, 中医药具有极好的防治作用 …
CLPC1 protein inhibition, antimycobacterial, and anti‐inflammatory properties of the metabolite from Streptomyces wuyuanensis collected in Nghe An province …
HTN Ni, PT Ninh, NT Dung, T Van Chien… - Vietnam Journal of …, 2024 - Wiley Online Library
Streptomyces wuyuanensis A79 was isolated from the soil samples collected in Quynh
Luong mangrove forest, Quynh Luu district, Nghe An province, Vietnam. This strain …
Luong mangrove forest, Quynh Luu district, Nghe An province, Vietnam. This strain …