The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions
Interleukin-10 (IL-10) is a pleiotropic cytokine that has a fundamental role in modulating
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …
inflammation and in maintaining cell homeostasis. It primarily acts as an anti-inflammatory …
Redefining autoimmune disorders' pathoetiology: implications for mood and psychotic disorders' association with neurodegenerative and classical autoimmune …
Although previously restricted to a limited number of medical conditions, there is a growing
appreciation that 'autoimmune'(or immune-mediated) processes are important aspects of a …
appreciation that 'autoimmune'(or immune-mediated) processes are important aspects of a …
[HTML][HTML] Современная концепция аутоиммунитета в ревматологии
ЕЛ Насонов - Научно-практическая ревматология, 2023 - cyberleninka.ru
В спектре механизмов хронического воспаления центральное место занимают два
фундаментальных патологических процесса-аутоиммунитет и аутовоспаление …
фундаментальных патологических процесса-аутоиммунитет и аутовоспаление …
Chimeric antigen receptor T cell therapy for autoimmune disease
JB Chung, JN Brudno, D Borie… - Nature Reviews …, 2024 - nature.com
Infusion of T cells engineered to express chimeric antigen receptors (CARs) that target B
cells has proven to be a successful treatment for B cell malignancies. This success inspired …
cells has proven to be a successful treatment for B cell malignancies. This success inspired …
Association of peripheral B cells and delirium: combined single-cell sequencing and Mendelian randomization analysis
S Tan, S Pan, L Wei, W Chen, B Pan, G Kong… - Frontiers in …, 2024 - frontiersin.org
Background Delirium seriously affects the prognosis of patients and greatly reduces the
ability to work and live. Peripheral inflammatory events may contribute to the development of …
ability to work and live. Peripheral inflammatory events may contribute to the development of …
Engineered biological nanoparticles as nanotherapeutics for tumor immunomodulation
JN Rahmat, J Liu, T Chen, ZH Li, Y Zhang - Chemical Society Reviews, 2024 - pubs.rsc.org
Biological nanoparticles, or bionanoparticles, are small molecules manufactured in living
systems with complex production and assembly machinery. The products of the assembly …
systems with complex production and assembly machinery. The products of the assembly …
Safety and efficacy of C. muridarum vaccines adjuvanted with CpG-1826 and four concentrations of Montanide-ISA-720-VG
It is recommended that the adjuvant Montanide ISA 720 VG be used at a concentration of
70% v/v. At this concentration, Montanide causes at the site of immunization a local …
70% v/v. At this concentration, Montanide causes at the site of immunization a local …
PLGA-Chitosan Encapsulated IL-10 Nanoparticles Modulate Chlamydia Inflammation in Mice
AN Yilma, R Sahu, P Subbarayan… - International Journal …, 2024 - Taylor & Francis
Introduction Interleukin-10 (IL-10) is a key anti-inflammatory mediator in protecting host from
over-exuberant responses to pathogens and play important roles in wound healing …
over-exuberant responses to pathogens and play important roles in wound healing …
Exploring the therapeutic opportunities of potassium channels for the treatment of rheumatoid arthritis
NE More, R Mandlik, S Zine, VS Gawali… - Frontiers in …, 2024 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that affects the
synovial joint, which leads to inflammation, loss of function, joint destruction, and disability …
synovial joint, which leads to inflammation, loss of function, joint destruction, and disability …
[HTML][HTML] Mapping cellular interactions from spatially resolved transcriptomics data
J Zhu, Y Wang, WY Chang, A Malewska, F Napolitano… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Cell-cell communication (CCC) is essential to how life forms and functions. However,
accurate, high-throughput mapping of how expression of all genes in one cell affects …
accurate, high-throughput mapping of how expression of all genes in one cell affects …