[HTML][HTML] Paracetamol use during pregnancy—a call for precautionary action

AZ Bauer, SH Swan, D Kriebel, Z Liew… - Nature Reviews …, 2021 - nature.com
Abstract Paracetamol (N-acetyl-p-aminophenol (APAP), otherwise known as
acetaminophen) is the active ingredient in more than 600 medications used to relieve mild to …

[HTML][HTML] Endocrine disruptors and the male reproductive system

JB Stukenborg, RT Mitchell, O Söder - Best Practice & Research Clinical …, 2021 - Elsevier
In recent years, there has been an increased incidence in several of the most common
reproductive disorders, including hypospadias and cryptorchidism in newborns, and …

Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety

A Zafeiri, RT Mitchell, DC Hay… - Human reproduction …, 2021 - academic.oup.com
BACKGROUND Analgesia during pregnancy is often necessary. Due to their widespread
availability, many mothers opt to use over-the-counter (OTC) analgesics. Those analgesic …

Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

DM Kristensen… - Proceedings of the …, 2018 - National Acad Sciences
Concern has been raised over increased male reproductive disorders in the Western world,
and the disruption of male endocrinology has been suggested to play a central role. Several …

Prenatal exposure to acetaminophen and children's language development at 30 months

CG Bornehag, A Reichenberg, MU Hallerback… - European …, 2018 - cambridge.org
Objective: To examine prenatal APAP exposure in relation to language development in
offspring at 30 months of age. Method: A population-based pregnancy cohort study including …

Organophosphate and pyrethroid pesticide exposures measured before conception and associations with time to pregnancy in Chinese couples enrolled in the …

Y Hu, L Ji, Y Zhang, R Shi, W Han, LA Tse… - Environmental …, 2018 - ehp.niehs.nih.gov
Background: Pesticides have been associated with reproductive disorders, but there is
limited research on pesticide exposures and human fertility. Objective: We aimed to …

[HTML][HTML] Exposome-wide association study of semen quality: systematic discovery of endocrine disrupting chemical biomarkers in fertility require large sample sizes

MK Chung, GMB Louis, K Kannan, CJ Patel - Environment international, 2019 - Elsevier
Objectives Exposome-wide association studies (EWAS) are a systematic and unbiased way
to investigate multiple environmental factors associated with phenotype. We applied EWAS …

Urinary concentrations of acetaminophen in young children in central and south China: Repeated measurements and associations with 8-hydroxy-guanosine and 8 …

Y Sun, Y Wan, Y Jiang, H Wang - Science of The Total Environment, 2021 - Elsevier
Acetaminophen (AAP) is the most widely used over-the-counter analgesic in the world; it is
also a metabolite of industrial chemical aniline. It may predispose individuals to oxidative …

[HTML][HTML] Suspect and non-target screening of ovarian follicular fluid and serum–identification of anthropogenic chemicals and investigation of their association to …

I Hallberg, M Plassmann, M Olovsson, J Holte… - … Science: Processes & …, 2021 - pubs.rsc.org
In this work, ultra-high performance liquid chromatography-high resolution (Orbitrap) mass
spectrometry-based suspect and non-target screening was applied to follicular fluid (n= 161) …

Toward capturing the exposome: exposure biomarker variability and coexposure patterns in the shared environment

MK Chung, K Kannan, GM Louis… - Environmental science & …, 2018 - ACS Publications
Many factors affect the variation in the exposome. We examined the influence of shared
household and partner's sex in relation to the variation in 128 endocrine disrupting chemical …