Functionally Tailored Metal–Organic Framework Coatings for Mediating Ti Implant Osseointegration

Y Zhang, Z Cheng, Z Liu, X Shen, C Cai… - Advanced …, 2023 - Wiley Online Library
Owing to their mechanical resilience and non‐toxicity, titanium implants are widely applied
as the major treatment modality for the clinical intervention against bone fractures. However …

Design and clinical application of injectable hydrogels for musculoskeletal therapy

Ø Øvrebø, G Perale, JP Wojciechowski… - Bioengineering & …, 2022 - Wiley Online Library
Musculoskeletal defects are an enormous healthcare burden and source of pain and
disability for individuals. With an aging population, the proportion of individuals living with …

NIR-II ratiometric lanthanide-dye hybrid nanoprobes doped bioscaffolds for in situ bone repair monitoring

P Pei, H Hu, Y Chen, S Wang, J Chen, J Ming… - Nano Letters, 2022 - ACS Publications
In situ monitoring of tissue regeneration progression is of primary importance to basic
medical research and clinical transformation. Despite significant progress in the field of …

Microlenses fabricated by two‐photon laser polymerization for cell imaging with non‐linear excitation microscopy

M Marini, A Nardini, R Martínez Vázquez… - Advanced Functional …, 2023 - Wiley Online Library
Non‐linear excitation microscopy offers several advantages for in‐vivo imaging compared to
conventional confocal techniques. However, tissue penetration can still be an issue due to …

One‐Pot Construction of Articular Cartilage‐Like Hydrogel Coating for Durable Aqueous Lubrication

J Huang, Y Tang, P Wang, H Zhou, H Li… - Advanced …, 2024 - Wiley Online Library
Articular cartilage has an appropriate multilayer structure and superior tribological properties
and provides a structural paradigm for design of lubricating materials. However, mimicking …

Imaging-guided/improved diseases management for immune-strategies and beyond

T Zhang, S Guo, F Li, X Lan, Y Jia, J Zhang… - Advanced Drug Delivery …, 2022 - Elsevier
Timely and accurate assessment and diagnosis are extremely important and beneficial for
all diseases, especially for some of the major human disease, such as cancers …

Dissecting the recruitment and self-organization of αSMA-positive fibroblasts in the foreign body response

M Parlani, ML Bedell, AG Mikos, P Friedl… - Science …, 2022 - science.org
The foreign body response (FBR) is a clinically relevant issue that can cause malfunction of
implanted medical devices by fibrotic encapsulation. Whereas inflammatory aspects of the …

Intravital microscopy for real-time monitoring of drug delivery and nanobiological processes

J Momoh, D Kapsokalyvas, M Vogt, S Hak… - Advanced Drug Delivery …, 2022 - Elsevier
Intravital microscopy (IVM) expands our understanding of cellular and molecular processes,
with applications ranging from fundamental biology to (patho) physiology and immunology …

A miniaturized imaging window to quantify intravital tissue regeneration within a 3D microscaffold in longitudinal studies

C Conci, E Jacchetti, L Sironi, L Gentili… - Advanced Optical …, 2022 - Wiley Online Library
The biocompatibility assessment of biomaterials or the dynamic response of implanted
constructs entails inflammatory events primary reflected in cell behavior at the …

Histological and Immunohistochemical Characterization of Osteoimmunological Processes in Scaffold-Guided Bone Regeneration in an Ovine Large Segmental …

R Finze, M Laubach, M Russo Serafini, U Kneser… - Biomedicines, 2023 - mdpi.com
Large-volume bone defect regeneration is complex and demands time to complete. Several
regeneration phases with unique characteristics, including immune responses, follow …