The best treatment for elderly patients with advanced non–small-cell lung cancer (NSCLC)
is still debated. To guide clinical management of these patients and suggest the priorities for …

Apoptosis is a critical defense mechanism against the formation and progression of cancer
and exhibits distinct morphological and biochemical traits. Targeting apoptotic pathways …

Purpose To evaluate the effect of BLP25 liposome vaccine (L-BLP25) on survival and
toxicity in patients with stage IIIB and IV non–small-cell lung cancer (NSCLC). Secondary …

CCL5 (previously called RANTES) is in the CC-chemokine family and plays a crucial role in
the migration and metastasis of human cancer cells. Besides, integrins are the major …

Astrocytes secrete growth factors that are both neuroprotective and supportive for the local
environment. Identified by glial fibrillary acidic protein (GFAP) expression, astrocytes exhibit …

Despite intense efforts to develop non-cytotoxic anticancer treatments, effective agents are
still not available. Therefore, novel apoptosis-inducing drug leads that may be developed …

Transforming growth factor-β1 (TGF-β1) plays a crucial role in adhesion and migration of
human cancer cells. Besides, integrins are the major adhesive molecules in mammalian …

Background: The increasing use of biomarkers as molecular determinants of
responsiveness to conventional chemotherapy or molecular targeted therapy has raised the …

The 30-amino acid antimicrobial peptide Cbf-K16 is a cathelicidin-BF (BF-30) Lys16 mutant
derived from the snake venom of Bungarus fasciatus. Our previous study found that BF-30 …

Ninety samples from the extracts of plants from traditional Chinese medicines were
screened for antitumor activity. Paeoniflorigenone (PFG) was isolated as an active …