Background Routine use of whole‐cell pertussis (wP) vaccines was suspended in some
countries in the 1970s and 1980s because of concerns about adverse effects. Following this …

Childhood immunization is one of the major public health measures of the 20th century and
is now receiving special attention from the Clinton administration. At the same time, some …

Objective: To assess the efficacy and safety of whole-cell and acellular pertussis vaccines
administered to children singly or within diphtheria, tetanus and pertussis (DTP) vaccines …

Objective. To evaluate within the first 6 months of birth the immunogenicity of a 3-component
acellular pertussis (aP) vaccine containing filamentous hemagglutinin (FHA), pertactine …

Adverse events after vaccine administration are commonly reported in the general
population and constitute a common problem in clinical practice. The most frequent …

A massive diphtheria epidemic in Eastern Europe has resulted in increased anxiety that this
disease could spread to other countries. This fear is realistic because there is a gap in the …

Background: This multicenter study was undertaken to investigate the serologic evidence of
antibodies to Bordetella pertussis toxin (IgG-PT) in children and adolescents. Methods: IgG …

To assess the safety, immunogenicity, and lot consistency of a five-component acellular
pertussis vaccine combined with diphtheria and tetanus toxoid (Connaught Laboratories …

Study design. In a double blind, multicenter study, 366 healthy children were randomly
allocated to receive a single injection of a 5-component acellular or a whole cell pertussis …

Objectives. To evaluate the safety and immunogenicity of Biken acellular pertussis vaccine
in combination with diphtheria and tetanus toxoid (Biken DTaP) vaccine administered to …