As synaptic vesicles fuse, they must continually be replaced with new docked, fusion-
competent vesicles to sustain neurotransmission. It has long been appreciated that vesicles …

Studies on synaptic proteins involved in neurotransmitter release often aim at distinguishing
between their roles in vesicle priming (the docking of synaptic vesicles to the plasma …

There has been considerable controversy about pre-versus postsynaptic expression of
memory-related long-term potentiation (LTP), with corresponding disputes about underlying …

Objective This study investigated the proteomic characteristics of cerebrospinal fluid (CSF)
in patients with varicella zoster virus (VZV) meningitis to understanding the pathogenesis of …

Vestigial dopaminergic cells in PD have selectivity for a sub-class of hypersensitive neurons
with the nigrostriatal dopamine (DA) tract. DA is modulated in pre-synaptic nerve terminals to …

The presynaptic SNARE-complex regulator complexin (Cplx) enhances the fusogenicity of
primed synaptic vesicles (SVs). Consequently, Cplx deletion impairs action potential-evoked …

Synapses serve as the points of communication between neurons, consisting primarily of
three components: the presynaptic membrane, synaptic cleft, and postsynaptic membrane …

Synaptogenesis is the final phase of axonal pathfinding. Its sequences of spatial and
temporal development in the immature nervous system are precisely timed and consistent …

Gene regulation in the hippocampus is fundamental for its development, synaptic plasticity,
memory formation, and adaptability. Comparisons of gene expression among different …

Background: Alzheimer's disease (AD) is associated with impaired cerebral circulation
which underscores diminished delivery of blood oxygen and nutrients to and throughout the …