[HTML][HTML] Late-life depression: Epidemiology, phenotype, pathogenesis and treatment before and during the COVID-19 pandemic

Y Zhao, X Wu, M Tang, L Shi, S Gong, X Mei… - Frontiers in …, 2023 - frontiersin.org
Late-life depression (LLD) is one of the most common mental disorders among the older
adults. Population aging, social stress, and the COVID-19 pandemic have significantly …

[HTML][HTML] What can clozapine's effect on neural oscillations tell us about its therapeutic effects? A scoping review and synthesis

N Raymond, P Lizano, S Kelly, R Hegde… - Biomarkers in …, 2022 - Elsevier
Clozapine, a drug effective in treatment resistant schizophrenia, can modulate the brain's
electrical activity as measured by an electroencephalogram (EEG). Past reviews have …

Morbidity due to disparity in pediatric electroconvulsive therapy.

M Ong, E Patterson, L Stewart, D Pierce, JR Smith - 2023 - psycnet.apa.org
Comments on an article by Jeremy Miller et al.(see record 2022-37028-001). Dr. Miller and
colleagues recently submitted a Letter to the Editor discussing current state laws that result …

Serum kynurenine metabolites might not be associated with risk factors of treatment-resistant schizophrenia

J Huang, P Zhang, Y Zhou, J Tong, Y Cui, S Tan… - Journal of Psychiatric …, 2022 - Elsevier
Background About a third of patients with schizophrenia do not respond adequately to
currently available antipsychotics and thus experiences symptoms of greater severity, known …

Evidence of pharmacogenetics-based fluvoxamine use as an add-on to clozapine treatment in psychiatry

U Mossé, B Chaumette, J Wils, L Imbert… - …, 2022 - Future Medicine
Pharmacological treatments used for psychiatric disorders, such as clozapine, demonstrate
large interindividual variability in terms of possible adverse effects and therapeutic benefit …

Обсессивно-компульсивная симптоматика, индуцированная применением клозапина (алгоритм коррекции)

ЕВ Андриенко, ЕС Мосолова - Современная Терапия …, 2023 - ctmd.psypharma.ru
Аннотация Обзорная статья посвящена оценке влияния клозапина на развитие
обсессивно-компульсивной симптоматики (ОКС) у пациентов с шизофренией, а также …

[HTML][HTML] Pharmacokinetics and Pharmacodynamics: A Comprehensive Analysis of the Absorption, Distribution, Metabolism, and Excretion of Psychiatric Drugs

Z Zakaraya, M Abu Assab, LN Tamimi, N Karameh… - Pharmaceuticals, 2024 - mdpi.com
The two main classifications of antidepressant medications are selective norepinephrine
reuptake inhibitors (SNRIs) and selective serotonin reuptake inhibitors (SSRIs). Out of the …

Clozapine Use in 22q11. 2 Deletion Syndrome: A Systematic Review of the Literature

MA Colijn - Journal of Clinical Psychopharmacology, 2024 - journals.lww.com
Background 22q11. 2 deletion syndrome confers significant risk for the development of
schizophrenia. While current recommendations regarding the management of psychotic …

Exploring the mechanisms of clozapine-induced blood–brain barrier dysfunction using untargeted metabolomics and cellular metabolism analysis

S Ngamratanapaiboon, N Srikornvit… - Environmental …, 2023 - Elsevier
Brain microvascular endothelial cells (BMVECs) from the blood–brain barrier form a highly
selective membrane that protects the brain from circulating blood and maintains a stable …

Late-Life Depressive Disorders

E Gregory, T Cheng, A Hategan - Geriatric Psychiatry: A Case-Based …, 2024 - Springer
Depressive disorder is one of the most common psychiatric disorders experienced by older
adults. The misconception that “feeling sad is part of normal aging” contributes to the …