[HTML][HTML] A standardized methanol extract of Eclipta prostrata (L.) L.(Asteraceae) reduces bronchial hyperresponsiveness and production of Th2 cytokines in a murine …

LJ de Freitas Morel, BC de Azevedo, F Carmona… - Journal of …, 2017 - Elsevier
Ethnopharmacological relevance Eclipta prostrata (L.) L.(Asteraceae) has been used in
Brazilian traditional medicine to treat asthma and other respiratory illnesses. Aims of the …

Anticoccidial effects of coumestans from Eclipta alba for sustainable control of Eimeria tenella parasitosis in poultry production

MG Michels, LCT Bertolini, AF Esteves, P Moreira… - Veterinary …, 2011 - Elsevier
The aim of this study was to evaluate the anticoccidial efficacy of a product containing
coumestans from Eclipta alba. Experimental conditions were set up as to reproduce the …

Biodiversity as a source of bioactive compounds against snakebites

C LS Guimaraes, LS Moreira-Dill… - Current medicinal …, 2014 - ingentaconnect.com
Snakebites are a frequently neglected public health issue in tropical and subtropical
countries. According to the World Health Organization, 5 million people are bitten annually …

β-keto amyrin isolated from Cryptostegia grandiflora R. br. inhibits inflammation caused by Daboia russellii viper venom: Direct binding of β-keto amyrin to …

KH Santhosh, V Krishna, K Kemparaju, H Manjunatha… - Toxicon, 2024 - Elsevier
The search for mechanism-based anti-inflammatory therapies is of fundamental importance
to avoid undesired off-target effects. Phospholipase A 2 (PLA 2) activity is a potential …

[HTML][HTML] Optimization of supercritical fluid extraction and HPLC identification of wedelolactone from Wedelia calendulacea by orthogonal array design

AA Patil, BS Sachin, PS Wakte, DB Shinde - Journal of Advanced Research, 2014 - Elsevier
The purpose of this work is to provide a complete study of the influence of operational
parameters of the supercritical carbon dioxide assisted extraction (SC CO 2 E) on yield of …

Wedelolactone, an anti-inflammatory botanical, interrupts c-Myc oncogenic signaling and synergizes with enzalutamide to induce apoptosis in prostate cancer cells

S Sarveswaran, R Ghosh, R Parikh, J Ghosh - Molecular cancer therapeutics, 2016 - AACR
The c-Myc gene encodes an oncoprotein transcription factor that is frequently upregulated in
almost all cancer types and is the subject of intense investigation for management of cancer …

The potential of Brazilian native plant species used in the therapy for snakebites: A literature review

EL Konrath, I Strauch, DD Boeff, MD Arbo - Toxicon, 2022 - Elsevier
Snakebite envenoming is a potentially fatal disease categorized as a neglected public
health issue for not receiving the appropriate attention from national and international health …

Pd-Catalyzed C–S Activation for [3+ 3] Annulation of 2-(Methylthio) benzofuran-3-carboxylates and 2-Hydroxyphenylboronic Acids: Synthesis of Coumestan …

J Liu, Y Liu, W Du, Y Dong, J Liu… - The Journal of Organic …, 2013 - ACS Publications
Pd-catalytic C–S activation was successfully applied to initiate the cross-coupling of (2-
methylthio-3-ester) benzofurans with 2-hydroxyphenylboronic acids and sequential …

[HTML][HTML] A randomized ethnomedicinal survey of snakebite treatment in southwestern parts of Bangladesh

MN Hasan, NK Azam, MN Ahmed… - Journal of traditional and …, 2016 - Elsevier
Snakebite is the single most important toxin-related injury, causing substantial mortality in
many parts of the Africa, Asia and the Americas. Incidence of snakebite is usually recorded …

Studies on the binding of wedelolactone to human serum albumin with multi-spectroscopic analysis, molecular docking and molecular dynamic simulation

Y Liu, Z Yuan, P Zhao, C Li, L Qin, T Zhao, X Zhu… - Biophysical …, 2024 - Elsevier
Wedelolactone (WEL) is a small molecule compound isolated from Eclipta prostrate L.,
which has been reported to possess various biological activities such as anti-hepatotoxicity …