Diabetes mellitus comprises a group of carbohydrate metabolism disorders that share a
common main feature of chronic hyperglycemia that results from defects of insulin secretion …

Endothelial cells have emerged as key players in SARS-CoV-2 infection and COVID-19
inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation …

Background: Quercetin, a major flavonol, wildly exists in plantage, which has been reported
to have an anti-apoptosis and anti-inflammation effects on vascular endothelial cells, but its …

Background: The transcription factor BACH1 (BTB and CNC homology 1) suppressed
endothelial cells (ECs) proliferation and migration and impaired angiogenesis in the …

The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …

Trimethylamine-N-oxide (TMAO) is generated in a microbial-mammalian co-metabolic
pathway mainly from the digestion of meat-containing food and dietary quaternary amines …

There is accumulating evidence that vascular inflammation plays critical roles in
pathophysiology of atherosclerosis. It is widely accepted that both innate and adaptive …

Insulin resistance (IR) and cardiovascular disease (CVD) represent two universal public
health hazards, especially in today's Western societies. A causal-effect relationship has …

Obesity has become a major risk factor for the development of chronic diseases such as
insulin resistance, type 2 diabetes mellitus, and cardiovascular disease. Moreover, obesity …

The role of inflammation in atherosclerosis has been recognized several decades ago and
existing treatments provide benefits in part through non-specific anti-inflammatory actions …