The diabetes mellitus–atherosclerosis connection: The role of lipid and glucose metabolism and chronic inflammation
Diabetes mellitus comprises a group of carbohydrate metabolism disorders that share a
common main feature of chronic hyperglycemia that results from defects of insulin secretion …
common main feature of chronic hyperglycemia that results from defects of insulin secretion …
[HTML][HTML] SARS-CoV-2 mediated endothelial dysfunction: the potential role of chronic oxidative stress
Endothelial cells have emerged as key players in SARS-CoV-2 infection and COVID-19
inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation …
inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation …
Quercetin inhibits TNF-α induced HUVECs apoptosis and inflammation via downregulating NF-kB and AP-1 signaling pathway in vitro
T Chen, X Zhang, G Zhu, H Liu, J Chen, Y Wang, X He - Medicine, 2020 - journals.lww.com
Background: Quercetin, a major flavonol, wildly exists in plantage, which has been reported
to have an anti-apoptosis and anti-inflammation effects on vascular endothelial cells, but its …
to have an anti-apoptosis and anti-inflammation effects on vascular endothelial cells, but its …
Deletion of BACH1 attenuates atherosclerosis by reducing endothelial inflammation
Background: The transcription factor BACH1 (BTB and CNC homology 1) suppressed
endothelial cells (ECs) proliferation and migration and impaired angiogenesis in the …
endothelial cells (ECs) proliferation and migration and impaired angiogenesis in the …
[HTML][HTML] Biological drug and drug delivery-mediated immunotherapy
The initiation and development of major inflammatory diseases, ie, cancer, vascular
inflammation, and some autoimmune diseases are closely linked to the immune system …
inflammation, and some autoimmune diseases are closely linked to the immune system …
Trimethylamine N-oxide in relation to cardiometabolic health—cause or effect?
C Papandreou, M Moré, A Bellamine - Nutrients, 2020 - mdpi.com
Trimethylamine-N-oxide (TMAO) is generated in a microbial-mammalian co-metabolic
pathway mainly from the digestion of meat-containing food and dietary quaternary amines …
pathway mainly from the digestion of meat-containing food and dietary quaternary amines …
[HTML][HTML] Critical roles of inflammation in atherosclerosis
J Moriya - Journal of cardiology, 2019 - Elsevier
There is accumulating evidence that vascular inflammation plays critical roles in
pathophysiology of atherosclerosis. It is widely accepted that both innate and adaptive …
pathophysiology of atherosclerosis. It is widely accepted that both innate and adaptive …
Insulin resistance and cardiovascular disease
CE Kosmas, MD Bousvarou… - Journal of …, 2023 - journals.sagepub.com
Insulin resistance (IR) and cardiovascular disease (CVD) represent two universal public
health hazards, especially in today's Western societies. A causal-effect relationship has …
health hazards, especially in today's Western societies. A causal-effect relationship has …
Modulation of chronic inflammation by quercetin: The beneficial effects on obesity
S Sato, Y Mukai - Journal of inflammation research, 2020 - Taylor & Francis
Obesity has become a major risk factor for the development of chronic diseases such as
insulin resistance, type 2 diabetes mellitus, and cardiovascular disease. Moreover, obesity …
insulin resistance, type 2 diabetes mellitus, and cardiovascular disease. Moreover, obesity …
[HTML][HTML] Targeting IL-1β in the Treatment of Atherosclerosis
W Mai, Y Liao - Frontiers in immunology, 2020 - frontiersin.org
The role of inflammation in atherosclerosis has been recognized several decades ago and
existing treatments provide benefits in part through non-specific anti-inflammatory actions …
existing treatments provide benefits in part through non-specific anti-inflammatory actions …