Cardiac fibrosis plays an indispensable role in cardiac tissue homeostasis and repair after
myocardial infarction (MI). The cardiac fibroblast-to-myofibroblast differentiation and …

Despite the availability of various therapeutic classes of antihypertensive drugs,
hypertension remains poorly controlled, in part due to poor adherence. Hence, there is a …

Background Preclinical data suggest that central renin-angiotensin system blockade by the
brain aminopeptidase-A inhibitor firibastat can improve left ventricular ejection fraction …

Aminopeptidases selectively hydrolyze an aminoacid residue from the amino terminus of
proteins and peptides resulting in their activation or inactivation. These enzymes are mainly …

Page 1 frontiers Research Topics Fibrosis: Etiology, pathophysiology, measurements, and
therapy Edited by Yuxia Zhao, Panpan Hao, Peizhe Wang, Fujian Lu and Yanping Liu …