Dendritic cells (DCs) represent a heterogeneous population of antigen-presenting cells that
initiate and orient immune responses in secondary lymphoid organs. In mice, lymphoid …

Dendritic cells play a key role in the orchestration of antitumor immune responses. The
cDC1 (conventional dendritic cell 1) subset has been shown to be essential for antitumor …

Dendritic cells (DCs) have the unique ability to pick up dead cells carrying antigens in tissue
and migrate to the lymph nodes where they can cross-present cell-associated antigens by …

The effective vaccines developed against a variety of infectious agents, including polio,
measles, and hepatitis B, represent major achievements in medicine. These vaccines …

Dendritic cells (DCs) play important roles in orchestrating host immunity against invading
pathogens, representing one of the first responders to infection by mucosal invaders. From …

Background The manipulation of dendritic cells (DCs) for cancer vaccination has not
reached its full potential, despite the revolution in cancer immunotherapy. DCs are …

Cytokine-based immunotherapy is a promising field in the cancer treatment, since cytokines,
as proteins of the immune system, are able to modulate the host immune response toward …

DNGR-1 (CLEC9A) is a receptor for necrotic cells required by DCs to cross-prime CTLs
against dead cell antigens in mice. It is currently unknown how DNGR-1 couples dead cell …

Human skin immune homeostasis, and its regulation by specialized subsets of tissue-
residing immune sentinels, is poorly understood. In this study, we identify an …

Dendritic cells (DC) represent a heterogeneous population of antigen-presenting cells that
are crucial in initiating and shaping immune responses. Although all DC are capable of …