Sex/gender differences in obesity prevalence, comorbidities, and treatment

AJ Cooper, SR Gupta, AF Moustafa, AM Chao - Current obesity reports, 2021 - Springer
Abstract Purpose of Review Obesity is a heterogeneous condition, yet sex/gender is rarely
considered in the prevention or clinical care of this disease. This review examined and …

Let's talk about sex: Differences in drug therapy in males and females

CM Madla, FKH Gavins, HA Merchant, M Orlu… - Advanced Drug Delivery …, 2021 - Elsevier
Abstract Professor Henry Higgins in My Fair Lady said,'Why can'ta woman be more like a
man?'Perhaps unintended, such narration extends to the reality of current drug …

[HTML][HTML] Sex differences in methamphetamine use disorder perused from pre-clinical and clinical studies: Potential therapeutic impacts

AP Daiwile, S Jayanthi, JL Cadet - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
Methamphetamine (METH) use, and misuse are associated with severe socioeconomic
consequences. METH users develop tolerance, lose control over drug taking behaviors, and …

Sex differences in heart failure

A Lala, U Tayal, CE Hamo, Q Youmans… - Journal of cardiac …, 2022 - Elsevier
Heart failure (HF) continues to be a major contributor of morbidity and mortality for men and
women alike, yet how the predisposition for, course and management of HF differ between …

Estrogen-mediated mechanisms in hypertension and other cardiovascular diseases

B Visniauskas, I Kilanowski-Doroh, BO Ogola… - Journal of human …, 2023 - nature.com
Cardiovascular disease (CVD) is the leading cause of death globally for men and women.
Premenopausal women have a lower incidence of hypertension and other cardiovascular …

Sex differences in energy metabolism: natural selection, mechanisms and consequences

F Mauvais-Jarvis - Nature Reviews Nephrology, 2024 - nature.com
Metabolic homeostasis operates differently in men and women. This sex asymmetry is the
result of evolutionary adaptations that enable women to resist loss of energy stores and …

Differences in the epidemiology, management and outcomes of kidney disease in men and women

NC Chesnaye, JJ Carrero, M Hecking… - Nature Reviews …, 2024 - nature.com
Improved understanding of differences in kidney disease epidemiology, management and
outcomes in men and women could help nephrologists to better meet the needs of their …

Heart–brain interactions in cardiac and brain diseases: why sex matters

A Rossi, N Mikail, S Bengs, A Haider… - European heart …, 2022 - academic.oup.com
Cardiovascular disease and brain disorders, such as depression and cognitive dysfunction,
are highly prevalent conditions and are among the leading causes limiting patient's quality …

Quantification of P-Glycoprotein in the gastrointestinal tract of humans and rodents: methodology, gut region, sex, and species matter

Y Mai, L Dou, Z Yao, CM Madla… - Molecular …, 2021 - ACS Publications
Intestinal efflux transporters affect the gastrointestinal processing of many drugs but further
data on their intestinal expression levels are required. Relative mRNA expression and …

Gender medicine: effects of sex and gender on cardiovascular disease manifestation and outcomes

V Regitz-Zagrosek, C Gebhard - Nature Reviews Cardiology, 2023 - nature.com
Despite a growing body of evidence, the distinct contributions of biological sex and the
sociocultural dimension of gender to the manifestations and outcomes of ischaemic heart …