[HTML][HTML] Multidrug resistance (MDR): A widespread phenomenon in pharmacological therapies

A Catalano, D Iacopetta, J Ceramella, D Scumaci… - Molecules, 2022 - mdpi.com
Multidrug resistance is a leading concern in public health. It describes a complex phenotype
whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic …

[HTML][HTML] Review on multiple facets of drug resistance: a rising challenge in the 21st century

M Saha, A Sarkar - Journal of xenobiotics, 2021 - mdpi.com
With the advancements of science, antibiotics have emerged as an amazing gift to the
human and animal healthcare sectors for the treatment of bacterial infections and other …

CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database

BP Alcock, W Huynh, R Chalil, KW Smith… - Nucleic acids …, 2023 - academic.oup.com
Abstract The Comprehensive Antibiotic Resistance Database (CARD; card. mcmaster. ca)
combines the Antibiotic Resistance Ontology (ARO) with curated AMR gene (ARG) …

[HTML][HTML] Increased detection of carbapenemase-producing enterobacterales bacteria in Latin America and the Caribbean during the COVID-19 pandemic

GR Thomas, A Corso, F Pasterán, J Shal… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
Abstract During 2020–2021, countries in Latin America and the Caribbean reported clinical
emergence of carbapenemase-producing Enterobacterales that had not been previously …

Key considerations on the potential impacts of the COVID-19 pandemic on antimicrobial resistance research and surveillance

J Rodríguez-Baño, GM Rossolini… - Transactions of the …, 2021 - academic.oup.com
Antibiotic use in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients
during the COVID-19 pandemic has exceeded the incidence of bacterial coinfections and …

Decreasing proportion of extended-spectrum beta-lactamase among E. coli infections during the COVID-19 pandemic in France

O Lemenand, T Coeffic, S Thibaut, MC Cotinat… - Journal of Infection, 2021 - Elsevier
Objectives We investigated the impact of the COVID-19 and national pandemic response on
the epidemiology of Extended Spectrum Beta-Lactamase producing E. coli (ESBL-E. coli) in …

[HTML][HTML] Efflux pump mediated antimicrobial resistance by staphylococci in health-related environments: challenges and the quest for inhibition

A Dashtbani-Roozbehani, MH Brown - Antibiotics, 2021 - mdpi.com
The increasing emergence of antimicrobial resistance in staphylococcal bacteria is a major
health threat worldwide due to significant morbidity and mortality resulting from their …

[HTML][HTML] Antimicrobial resistance in Antarctica: is it still a pristine environment?

K Hwengwere, H Paramel Nair… - …, 2022 - microbiomejournal.biomedcentral …
Although the rapid spread of antimicrobial resistance (AMR), particularly in relation to
clinical settings, is causing concern in many regions of the globe, remote, extreme …

Clostridioides difficile infection (CDI) during the COVID-19 pandemic

P Spigaglia - Anaerobe, 2022 - Elsevier
The ongoing coronavirus disease (COVID-19) pandemic has dramatically tested healthcare
systems around the world, with serious repercussions on the measures of prevention and …

[HTML][HTML] Evaluation of bi-lateral co-infections and antibiotic resistance rates among COVID-19 patients

N Ahmed, M Khan, W Saleem, MI Karobari… - Antibiotics, 2022 - mdpi.com
In addition to the pathogenesis of SARS-CoV-2, bacterial co-infection plays an essential role
in the incidence and progression of SARS-CoV-2 infections by increasing the severity of …