Interaction between drugs and the gut microbiome
The human gut microbiome is a complex ecosystem that can mediate the interaction of the
human host with their environment. The interaction between gut microbes and commonly …
human host with their environment. The interaction between gut microbes and commonly …
[HTML][HTML] The association between early-life gut microbiota and long-term health and diseases
Early life gut microbiota have been increasingly recognized as major contributors to short
and/or long-term human health and diseases. Numerous studies have demonstrated that …
and/or long-term human health and diseases. Numerous studies have demonstrated that …
[HTML][HTML] Influence of the microbiome, diet and genetics on inter-individual variation in the human plasma metabolome
The levels of the thousands of metabolites in the human plasma metabolome are strongly
influenced by an individual's genetics and the composition of their diet and gut microbiome …
influenced by an individual's genetics and the composition of their diet and gut microbiome …
The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk
To address how the microbiome might modify the interaction between diet and
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …
cardiometabolic health, we analyzed longitudinal microbiome data from 307 male …
Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals
The gut microbiome is shaped by diet and influences host metabolism; however, these links
are complex and can be unique to each individual. We performed deep metagenomic …
are complex and can be unique to each individual. We performed deep metagenomic …
Association of insulin resistance and type 2 diabetes with gut microbial diversity: a microbiome-wide analysis from population studies
Z Chen, D Radjabzadeh, L Chen… - JAMA network …, 2021 - jamanetwork.com
Importance Previous studies have indicated that gut microbiome may be associated with
development of type 2 diabetes. However, these studies are limited by small sample size …
development of type 2 diabetes. However, these studies are limited by small sample size …
[HTML][HTML] An online atlas of human plasma metabolite signatures of gut microbiome composition
Human gut microbiota produce a variety of molecules, some of which enter the bloodstream
and impact health. Conversely, dietary or pharmacological compounds may affect the …
and impact health. Conversely, dietary or pharmacological compounds may affect the …
[HTML][HTML] The long-term genetic stability and individual specificity of the human gut microbiome
By following up the gut microbiome, 51 human phenotypes and plasma levels of 1,183
metabolites in 338 individuals after 4 years, we characterize microbial stability and variation …
metabolites in 338 individuals after 4 years, we characterize microbial stability and variation …
[HTML][HTML] Microbiome and metabolome features of the cardiometabolic disease spectrum
S Fromentin, SK Forslund, K Chechi… - Nature medicine, 2022 - nature.com
Previous microbiome and metabolome analyses exploring non-communicable diseases
have paid scant attention to major confounders of study outcomes, such as common, pre …
have paid scant attention to major confounders of study outcomes, such as common, pre …
[HTML][HTML] The gut microbiota-bile acid axis links the positive association between chronic insomnia and cardiometabolic diseases
Z Jiang, L Zhuo, Y He, Y Fu, L Shen, F Xu… - Nature …, 2022 - nature.com
Evidence from human cohorts indicates that chronic insomnia is associated with higher risk
of cardiometabolic diseases (CMD), yet whether gut microbiota plays a role is unclear. Here …
of cardiometabolic diseases (CMD), yet whether gut microbiota plays a role is unclear. Here …