Ebola virus disease

ST Jacob, I Crozier, WA Fischer, A Hewlett… - Nature reviews Disease …, 2020 - nature.com
Ebola virus disease (EVD) is a severe and frequently lethal disease caused by Ebola virus
(EBOV). EVD outbreaks typically start from a single case of probable zoonotic transmission …

Bench-to-bedside: Innovation of small molecule anti-SARS-CoV-2 drugs in China

L Yang, Z Wang - European journal of medicinal chemistry, 2023 - Elsevier
The ongoing COVID-19 pandemic has resulted in millions of deaths globally, highlighting
the need to develop potent prophylactic and therapeutic strategies against SARS-CoV-2 …

Prolonged severe acute respiratory syndrome coronavirus 2 replication in an immunocompromised patient

JH Baang, C Smith, C Mirabelli… - The Journal of …, 2021 - academic.oup.com
We describe a case of chronic coronavirus disease 2019 (COVID-19) in a patient with
lymphoma and associated B-cell immunodeficiency. Viral cultures and sequence analysis …

[HTML][HTML] Remdesivir as a possible therapeutic option for the COVID-19

JA Al-Tawfiq, AH Al-Homoud… - Travel medicine and …, 2020 - ncbi.nlm.nih.gov
In a recent review article, there were multiple preventive measures that were proposed for
the Middle East Respiratory Syndrome Coronavirus (MERS-CoV)[1]. Since 2002, we had …

Coronavirus disease 2019 treatment: a review of early and emerging options

EK McCreary, JM Pogue - Open forum infectious diseases, 2020 - academic.oup.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus
disease 2019 (COVID-19), has spread across the globe resulting in a pandemic. At the time …

Pharmacologic treatments for coronavirus disease 2019 (COVID-19): a review

JM Sanders, ML Monogue, TZ Jodlowski, JB Cutrell - Jama, 2020 - jamanetwork.com
Importance The pandemic of coronavirus disease 2019 (COVID-19) caused by the novel
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents an …

Prophylactic and therapeutic remdesivir (GS-5734) treatment in the rhesus macaque model of MERS-CoV infection

E De Wit, F Feldmann, J Cronin… - Proceedings of the …, 2020 - National Acad Sciences
The continued emergence of Middle East Respiratory Syndrome (MERS) cases with a high
case fatality rate stresses the need for the availability of effective antiviral treatments …

Arguments in favour of remdesivir for treating SARS-CoV-2 infections

WC Ko, JM Rolain, NY Lee, PL Chen, CT Huang… - International journal of …, 2020 - Elsevier
Since the end of 2019, an increasing number of cases of pneumonia were reported in
Wuhan, followed by other cities and provinces in China and many other countries …

COVID-19 false dichotomies and a comprehensive review of the evidence regarding public health, COVID-19 symptomatology, SARS-CoV-2 transmission, mask …

K Escandón, AL Rasmussen, II Bogoch… - BMC infectious …, 2021 - Springer
Scientists across disciplines, policymakers, and journalists have voiced frustration at the
unprecedented polarization and misinformation around coronavirus disease 2019 (COVID …

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses

TP Sheahan, AC Sims, RL Graham… - Science translational …, 2017 - science.org
Emerging viral infections are difficult to control because heterogeneous members
periodically cycle in and out of humans and zoonotic hosts, complicating the development of …