[HTML][HTML] Recent advances in drug delivery systems for targeting cancer stem cells
H Duan, Y Liu, Z Gao, W Huang - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Cancer stem cells (CSCs) are a subpopulation of cancer cells with functions similar to those
of normal stem cells. Although few in number, they are capable of self-renewal, unlimited …
of normal stem cells. Although few in number, they are capable of self-renewal, unlimited …
Nano-delivery to the lung-by inhalation or other routes and why nano when micro is largely sufficient?
V Forest, J Pourchez - Advanced Drug Delivery Reviews, 2022 - Elsevier
Respiratory diseases gather a wide range of disorders which are generally difficult to treat,
partly due to a poor delivery of drugs to the lung with adequate dose and minimum side …
partly due to a poor delivery of drugs to the lung with adequate dose and minimum side …
Recent advances in the surface functionalization of PLGA-based nanomedicines
MM El-Hammadi, JL Arias - Nanomaterials, 2022 - mdpi.com
Therapeutics are habitually characterized by short plasma half-lives and little affinity for
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …
targeted cells. To overcome these challenges, nanoparticulate systems have entered into …
Downregulated exosomal microRNA-148b-3p in cancer associated fibroblasts enhance chemosensitivity of bladder cancer cells by downregulating the Wnt/β-catenin …
G Shan, X Zhou, J Gu, D Zhou, W Cheng, H Wu… - Cellular Oncology, 2021 - Springer
Objective Exosomes derived from cancer-associated fibroblasts (CAFs) are known as
important drivers of tumor progression. Previously, microRNA (miR)-148b-3p has been …
important drivers of tumor progression. Previously, microRNA (miR)-148b-3p has been …
Anti-lung cancer effect of paclitaxel solid lipid nanoparticles delivery system with curcumin as co-loading partner in vitro and in vivo
C Pi, W Zhao, M Zeng, J Yuan, H Shen, K Li, Z Su… - Drug Delivery, 2022 - Taylor & Francis
The main aim of this study was to improve the therapeutic potential of a paclitaxel (PTX) and
curcumin (CU) combination regimen using solid lipid nanoparticles (SLNs). PTX and CU …
curcumin (CU) combination regimen using solid lipid nanoparticles (SLNs). PTX and CU …
Targeted delivery of paclitaxel drug using polymer-coated magnetic nanoparticles for fibrosarcoma therapy: in vitro and in vivo studies
Fibrosarcoma is a rare type of cancer that affects cells known as fibroblasts that are
malignant, locally recurring, and spreading tumor in fibrous tissue. In this work, an iron plate …
malignant, locally recurring, and spreading tumor in fibrous tissue. In this work, an iron plate …
Recent applications and strategies in nanotechnology for lung diseases
W Zhong, X Zhang, Y Zeng, D Lin, J Wu - Nano Research, 2021 - Springer
Lung diseases, including COVID-19 and lung cancers, is a huge threat to human health.
However, for the treatment and diagnosis of various lung diseases, such as pneumonia …
However, for the treatment and diagnosis of various lung diseases, such as pneumonia …
Enhanced cancer-targeted drug delivery using precoated nanoparticles
L Yu, M Xu, W Xu, W Xiao, XH Jiang, L Wang… - Nano Letters, 2020 - ACS Publications
While protein coronas (PCs) are an important barrier in the clinical application of
nanomedicines, the specific effects of PCs on nanoparticles (NPs) in vivo are unclear …
nanomedicines, the specific effects of PCs on nanoparticles (NPs) in vivo are unclear …
[HTML][HTML] Colon cancer therapy with calcium phosphate nanoparticles loading bioactive compounds from Euphorbia lathyris: In vitro and in vivo assay
Amorphous calcium phosphate nanoparticles (ACP NPs) exhibit excellent biocompatibility
and biodegradability properties. ACP NPs were functionalized with two coumarin …
and biodegradability properties. ACP NPs were functionalized with two coumarin …
A pH/ROS-responsive, tumor-targeted drug delivery system based on carboxymethyl chitin gated hollow mesoporous silica nanoparticles for anti-tumor chemotherapy
X Ding, W Yu, Y Wan, M Yang, C Hua, N Peng… - Carbohydrate …, 2020 - Elsevier
A new nanosystem was prepared by coating ROS-cleavable thioketal (TK) bonded hollow
mesoporous silica nanoparticles with carboxymethyl chitin via electrostatic interaction and …
mesoporous silica nanoparticles with carboxymethyl chitin via electrostatic interaction and …