Alzheimer's disease (AD) is characterized by the accumulation of extracellular Aβ42 and
Aβ40 oligomers and plaques. In a recent computational study, we found that the presence of …

Amyloid-β oligomer (AβO) is believed to cause neurotoxicity which is linked to Alzheimer's
disease (AD). Therefore, the detection of AβO has been proposed as an effective method for …

In this work, an ultra-sensitive amyloid beta oligomer (AβO) sensor is presented in the
detection range at atomolar level. A hierarchical gold dendrite (AuD) was electrochemically …

Alzheimer's disease (AD), an age-related neurodegenerative disease, the most common
causes of dementia is a multifactorial pathology categorized by a complex etiology …

Caffeine and its derivatives can effectively bind amyloid beta 16–22 (Aβ16–22) fragment of
amyloid beta 1–42 (Aβ1–42), a biomarker for the early diagnosis of Alzheimer's disease …

An important measure of the conformation of protein molecules is the degree of surface
exposure of its specific segments. However, this is hard to measure at the level of individual …

The interaction of disease-causing amyloid oligomers with lipid membranes is implicated in
their toxicity. However, understanding the membrane interaction of different oligomers, and …

Experimental studies have reported that the amyloid-β proteins can form pores in cell
membranes, and this could be one possible source of toxicity in Alzheimer's disease …

Neurodegenerative diseases (NDs) have been a major threat to human especially for
elders. Despite a rapid increase in the severity and prevalence of the disease, early …

Metallic materials have been one of the most ancient themes of study. Metals that account
for 24% of the mass of the planet and about two-thirds of the elements occupy a unique …