[HTML][HTML] Insect-pathogen crosstalk and the cellular-molecular mechanisms of insect immunity: uncovering the underlying signaling pathways and immune regulatory …

DK Mahanta, TK Bhoi, J Komal, I Samal… - Frontiers in …, 2023 - frontiersin.org
Multicellular organisms are constantly subjected to pathogens that might be harmful.
Although insects lack an adaptive immune system, they possess highly effective anti …

[PDF][PDF] Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

MA Hanson, B Lemaitre - Disease Models & Mechanisms, 2023 - journals.biologists.com
Antimicrobial peptides (AMPs) are innate immune effectors first studied for their role in host
defence. Recent studies have implicated these peptides in the clearance of aberrant cells …

[HTML][HTML] The genetic basis of variation in immune defense against Lysinibacillus fusiformis infection in Drosophila melanogaster

BR Smith, KB Patch, A Gupta, EM Knoles… - PLoS …, 2023 - journals.plos.org
The genetic causes of phenotypic variation often differ depending on the population
examined, particularly if the populations were founded by relatively small numbers of …

Single innate immune effectors control ecological microbiome bacteria across evolutionary timescales

MA Hanson, L Grollmus, B Lemaitre - bioRxiv, 2022 - biorxiv.org
Antimicrobial peptides are host-encoded antibiotics that combat invading microbes and help
shape the microbiome in plants and animals. However, little is known about how the host …