Inflammatory bowel disease (IBD) comprises ulcerative colitis (UC) and Crohn's disease
(CD). IBD etiopathology is multifactorial and involves alteration of immune cells and chronic …

An effective resolution program may be able to prevent the progression from non-resolving
acute inflammation to persistent chronic inflammation. It has now become evident that …

Uncontrolled inflammation is a leading cause of many clinically relevant diseases. Current
therapeutic strategies focus mainly on immunosuppression rather than on the mechanisms …

Glucocorticoid hormones regulate essential body functions in mammals, control cell
metabolism, growth, differentiation, and apoptosis. Importantly, they are potent suppressors …

The termination of inflammation is governed by endogenous molecules collectively referred
to as 'mediators of resolution'of inflammation. There is now strong evidence to suggest that …

Chronic diseases that affect our society are made more complex by comorbidities and are
poorly managed by the current pharmacology. While all present inflammatory …

Our interest in inflammation and its treatment stems from ancient times. Hippocrates used
willow bark to treat inflammation, and many centuries later, salicylic acid and its derivative …

The control of inflammation is strictly regulated to ensure the adequate intensity and duration
of an inflammatory response, enabling the removal of the trigger factors and the restoration …

Abstract Coronavirus Disease 19 (COVID-19) is associated with high morbidity and mortality
rates globally, representing the greatest health and economic challenge today. Several …

Glucocorticoid-induced leucine zipper (GILZ) is a dexamethasone-inducible gene that
mediates glucocorticoid (GC) actions in a variety of cell types, including many cells of …