Sepsis, severe sepsis, and septic shock represent increasingly severe systemic
inflammatory responses to infection. Sepsis is common in the aging population, and it …

Anti-infective biomaterials need to be tailored according to the specific clinical application.
All their properties have to be tuned to achieve the best anti-infective performance together …

Previously published guidelines are available that provide comprehensive
recommendations for detecting and preventing healthcare-associated infections (HAIs). The …

Biofilms are a complex group of microbial cells that adhere to the exopolysaccharide matrix
present on the surface of medical devices. Biofilm-associated infections in the medical …

Healthcare-associated infections (HAIs) are caused by nosocomial pathogens. HAIs have
an immense impact not only on developing countries but also on highly developed parts of …

National evidence-based guidelines for preventing healthcare-associated infections (HCAI)
in National Health Service (NHS) hospitals in England were originally commissioned by the …

Cancer patients frequently require central venous catheters for therapy and parenteral
nutrition and are at high risk of central venous catheter–related infections (CRIs). Moreover …

Though biofilms were first described by Antonie van Leeuwenhoek, the theory describing
the biofilm process was not developed until 1978. We now understand that biofilms are …

Biofilms—matrix-enclosed microbial accretions that adhere to biological or non-biological
surfaces—represent a significant and incompletely understood mode of growth for bacteria …

Naomi P. O'Grady, 1 Mary Alexander, 2 Lillian A. Burns, 3 E. Patchen Dellinger, 4 Jeffrey
Garland, 5 Stephen O. Heard, 6 Pamela A. Lipsett, 7 Henry Masur, 1 Leonard A. Mermel, 8 …