Sex-specific IL-6-associated signaling activation in ozone-induced lung inflammation

V Mishra, SL DiAngelo, P Silveyra - Biology of sex differences, 2016 - Springer
Background Acute ozone (O 3) exposure has known deleterious effects on the respiratory
system and has been linked with respiratory disease and infection. Inflammatory lung …

Sex difference in the morbidity and pain response with stage 0 of medication-related osteonecrosis of the jaws

W Zhang, R Gao, Y Cui, F Ding, S Zhu, S Luo… - Journal of Oral …, 2023 - Elsevier
Objective Medication-related osteonecrosis of the jaws (MRONJ) is a potentially severe
complication associated with antiresorptive or antiangiogenic therapies. Prior studies …

Microvesicle-derived miRNAs regulate proinflammatory macrophage activation in the lung following ozone exposure

JM Carnino, H Lee, LC Smith, VR Sunil… - Toxicological …, 2022 - academic.oup.com
Ozone is a ubiquitous air pollutant that causes lung damage and altered functioning.
Evidence suggests that proinflammatory macrophages contribute to ozone toxicity. Herein …

Compartment-specific transcriptomics of ozone-exposed murine lungs reveals sex-and cell type-associated perturbations relevant to mucoinflammatory lung diseases

I Choudhary, T Vo, K Paudel… - American Journal of …, 2021 - journals.physiology.org
Ozone is known to cause lung injury, and resident cells of the respiratory tract (ie, epithelial
cells and macrophages) respond to inhaled ozone in a variety of ways that affect their …

Role of innate immune system in environmental lung diseases

MA Guttenberg, AT Vose, RM Tighe - Current allergy and asthma reports, 2021 - Springer
The lung mucosa functions as a principal barrier between the body and inhaled
environmental irritants and pathogens. Precise and targeted surveillance mechanisms are …

Role of PPARγ in dyslipidemia and altered pulmonary functioning in mice following ozone exposure

LC Smith, AJ Gow, E Abramova, K Vayas… - Toxicological …, 2023 - academic.oup.com
Exposure to ozone causes decrements in pulmonary function, a response associated with
alterations in lung lipids. Pulmonary lipid homeostasis is dependent on the activity of …

Transcriptional profiling of the murine airway response to acute ozone exposure

A Tovar, GJ Smith, JM Thomas, WL Crouse… - Toxicological …, 2020 - academic.oup.com
Ambient ozone (O3) exposure has serious consequences on respiratory health, including
airway inflammation and injury. Decades of research have yielded thorough descriptions of …

Identification of a Gene Signature Predicting (Nano) Particle-Induced Adverse Lung Outcome in Rats

SA Valentino, C Seidel, M Lorcin, S Sébillaud… - International Journal of …, 2023 - mdpi.com
Nanoparticles are extensively used in industrial products or as food additives. However,
despite their contribution to improving our quality of life, concerns have been raised …

Acute and repeated ozone exposures differentially affect circadian clock gene expression in mice

IK Sundar, SK Duraisamy, I Choudhary… - Advanced …, 2023 - Wiley Online Library
Circadian rhythms have an established role in regulating physiological processes, such as
inflammation, immunity, and metabolism. Ozone, a common environmental pollutant with …

Relationships between long-term ozone exposure and allergic rhinitis and bronchitic symptoms in Chinese children

PE Zhou, Z Qian, SE McMillin, MG Vaughn, ZY Xie… - Toxics, 2021 - mdpi.com
Numerous studies have demonstrated that exposure to ambient ozone (O3) could have
adverse effects on children's respiratory health. However, previous studies mainly focused …