[HTML][HTML] Factors affecting the formation and treatment of thrombosis by natural and synthetic compounds

A Lichota, EM Szewczyk, K Gwozdzinski - International journal of …, 2020 - mdpi.com
Venous thromboembolism (VTE) refers to deep vein thrombosis (DVT), whose consequence
may be a pulmonary embolism (PE). Thrombosis is associated with significant morbidity and …

[HTML][HTML] In silico design, docking simulation, and ANN-QSAR model for predicting the anticoagulant activity of thiourea isosteviol compounds as FXa inhibitors

M Gackowski, B Madriwala, M Koba - Chemical Papers, 2023 - Springer
Novel oral anticoagulants are frequently used for the pharmacotherapy of thromboembolic
disorders but still have drawbacks and side effects. While numerous synthetic and …

[HTML][HTML] Direct Oral FXa Inhibitors Binding to Human Serum Albumin: Spectroscopic, Calorimetric, and Computational Studies

N Mariño-Ocampo, DF Rodríguez… - International Journal of …, 2023 - mdpi.com
Direct FXa inhibitors are an important class of bioactive molecules (rivaroxaban, apixaban,
edoxaban, and betrixaban) applied for thromboprophylaxis in diverse cardiovascular …

[HTML][HTML] Applied nanotechnologies in anticoagulant therapy: from anticoagulants to coagulation test performance of drug delivery systems

YBG Patriota, LL Chaves, EH Gocke, P Severino… - Applied Nano, 2021 - mdpi.com
Heparin-based delivery systems have been explored to improve their therapeutic efficacy
and to reduce toxicity for different administration routes. Regardless of the applied drug …

[PDF][PDF] Applied Nanotechnologies in Anticoagulant Therapy: From Anticoagulants to Coagulation Test Performance of Drug Delivery Systems. Appl. Nano. 2021; 2 (2) …

Y Patriota, L Chaves, E Gocke, P Severino, M Soares… - 2021 - core.ac.uk
Heparin-based delivery systems have been explored to improve their therapeutic efficacy
and to reduce toxicity for different administration routes. Regardless of the applied drug …

[PDF][PDF] ABRAR HUSSAIN

Z KHAN - researchgate.net
Factor X is one of the main enzymes in blood coagulation cascade. It is present at the middle
point of intrinsic and extrinsic pathways and become activated once an injury occur. Its basic …