To fulfill the task of gas exchange, the lung possesses a huge inner surface and a tree-like
system of conducting airways ventilating the gas exchange area. During lung development …

Respiratory disease is the third leading cause of death in the industrialized world.
Consequently, the trachea, lungs, and cardiopulmonary vasculature have been the focus of …

To investigate the role of immune cells in lung regeneration, we used a unilateral
pneumonectomy model that promotes the formation of new alveoli in the remaining lobes …

Structural and functional complexities of the mammalian lung evolved to meet a unique set
of challenges, namely, the provision of efficient delivery of inspired air to all lung units within …

Organoids are derived from stem cells or organ-specific progenitors. They display structures
and functions consistent with organs in vivo. Multiple types of organoids, including lung …

The tissue turnover of unperturbed adult lung is remarkably slow. However, after injury or
insult, a specialised group of facultative lung progenitors become activated to replenish …

Design-based stereology is the gold standard of morphometry in lung research. Here, we
analyze the current use of morphometric and stereological methods in lung research and …

This review compares the manner in which physical stress imposed on the parenchyma,
vasculature and thorax and the thoraco-pulmonary interactions, drive both developmental …

Pulmonary and systemic insults from inhalation injury can complicate the care of burn
patients and contribute to significant morbidity and mortality. However, recent progress in …

The SU5416+ hypoxia (SuHx) rat model is a commonly used model of severe pulmonary
arterial hypertension. While it is known that exposure to hypoxia can be replaced by another …