Pre-referral rectal artesunate suppositories can save the lives of children with severe
malaria if patients receive adequate post-referral care. A multi-country randomised …

Background To prevent child deaths from severe malaria, early parenteral treatment is
essential. Yet, in remote rural areas, accessing facilities offering parenteral antimalarials …

Background Health facilities' availability of malaria diagnostic tests and anti-malarial drugs
(AMDs), and the correctness of treatment are critical for the appropriate case management …

The key to reducing malaria deaths in highly endemic areas is prompt access to quality case
management. Given that many severe cases occur at peripheral level, rectal artesunate …

Introduction Children who receive prereferral rectal artesunate (RAS) require urgent referral
to a health facility where appropriate treatment for severe malaria can be provided …

Background Rectal artesunate, an efficacious pre-referral treatment for severe malaria in
children, was deployed at scale in Uganda, Nigeria, and DR Congo. In addition to …

Administering rectal artesunate suppositories to patients with severe malaria before they
receive parenteral and oral consolidation therapy was found to reduce mortality more than a …

Background Malaria remains a major public health issue in the Democratic Republic of the
Congo (DRC), accounting for 44% deaths among outpatient visits in children< 5 years of …

Background Severe malaria is a life-threatening infection, particularly affecting children
under the age of 5 years in Africa. Current treatment with parenteral artemisinin derivatives …

Background Nonadherence to national standards for malaria diagnosis and treatment has
been reported in Sudan. In this study, qualitative research examined the clinical domains of …