The extracellular matrix in skin inflammation and infection
K Pfisterer, LE Shaw, D Symmank… - Frontiers in cell and …, 2021 - frontiersin.org
The extracellular matrix (ECM) is an integral component of all organs and plays a pivotal
role in tissue homeostasis and repair. While the ECM was long thought to mostly have …
role in tissue homeostasis and repair. While the ECM was long thought to mostly have …
Tumor-derived exosomes in the regulation of macrophage polarization
Background This review focuses on exosomes derived from various cancer cells. The review
discusses the possibility of differentiating macrophages in alternatively activated anti …
discusses the possibility of differentiating macrophages in alternatively activated anti …
Adhesive composite hydrogel patch for sustained transdermal drug delivery to treat atopic dermatitis
YE Kim, HY Jung, N Park, J Kim - Chemistry of Materials, 2023 - ACS Publications
Atopic dermatitis (AD) is a common chronic inflammatory skin disease. Continuous
administration of steroids often causes undesired side effects; hence, drug delivery systems …
administration of steroids often causes undesired side effects; hence, drug delivery systems …
Bioinspired and inflammation‐modulatory glycopeptide hydrogels for radiation‐induced chronic skin injury repair
Z Feng, Y Zhang, C Yang, X Liu… - Advanced …, 2023 - Wiley Online Library
Clinical wound management of radiation‐induced skin injury (RSI) remains a great
challenge due to acute injuries induced by excessive reactive oxygen species (ROS), and …
challenge due to acute injuries induced by excessive reactive oxygen species (ROS), and …
Extracellular matrix stiffness—The central cue for skin fibrosis
K Wang, D Wen, X Xu, R Zhao, F Jiang… - Frontiers in Molecular …, 2023 - frontiersin.org
Skin fibrosis is a physiopathological process featuring the excessive deposition of
extracellular matrix (ECM), which is the main architecture that provides structural support …
extracellular matrix (ECM), which is the main architecture that provides structural support …
Alarmin cytokines as central regulators of cutaneous immunity
T Hasegawa, T Oka, S Demehri - Frontiers in Immunology, 2022 - frontiersin.org
Skin acts as the primary interface between the body and the environment. The skin immune
system is composed of a complex network of immune cells and factors that provide the first …
system is composed of a complex network of immune cells and factors that provide the first …
Notch-ing up knowledge on molecular mechanisms of skin fibrosis: focus on the multifaceted Notch signalling pathway
AG Condorelli, M El Hachem, G Zambruno… - Journal of Biomedical …, 2021 - Springer
Fibrosis can be defined as an excessive and deregulated deposition of extracellular matrix
proteins, causing loss of physiological architecture and dysfunction of different tissues and …
proteins, causing loss of physiological architecture and dysfunction of different tissues and …
Robust temporal map of human in vitro myelopoiesis using single-cell genomics
Myeloid cells are central to homeostasis and immunity. Characterising in vitro myelopoiesis
protocols is imperative for their use in research, immunotherapies, and understanding …
protocols is imperative for their use in research, immunotherapies, and understanding …
Wound healing across the animal kingdom: crosstalk between the immune system and the extracellular matrix
CM Arenas Gómez, KZ Sabin… - Developmental …, 2020 - Wiley Online Library
Tissue regeneration is widespread in the animal kingdom. To date, key roles for different
molecular and cellular programs in regeneration have been described, but the ultimate …
molecular and cellular programs in regeneration have been described, but the ultimate …
Mechanotransduction in skin inflammation
MS Shutova, WH Boehncke - Cells, 2022 - mdpi.com
In the process of mechanotransduction, the cells in the body perceive and interpret
mechanical stimuli to maintain tissue homeostasis and respond to the environmental …
mechanical stimuli to maintain tissue homeostasis and respond to the environmental …