The adventitial layer surrounding the blood vessels has long been exclusively considered a
supporting tissue the main function of which is to provide adequate nourishment to the …

Animal models are designed to be preliminary tools for better understanding of the
pathogenesis, improvement in diagnosis, prevention, and therapy of arteriosclerosis in …

We present a computational framework for multiscale modeling and simulation of blood flow
in coronary artery bypass graft (CABG) patients. Using this framework, only CT and non …

To examine the role of heme oxygenase (HO)‐1 in the pathophysiology of vascular
diseases, we generated mice deficient in both HO‐1 and apolipoprotein E (HO‐1 …

Previously we showed that a large number of endothelial cells in vein grafts undergo
apoptosis or necrosis during the first few days followed by endothelial regeneration. In the …

Importance Intimal hyperplasia and subsequent saphenous vein graft failure may have
significant adverse clinical effects in patients undergoing coronary artery bypass surgery …

Objective: Autologous endothelial cell seeding was used to improve the patency of 4-mm
polytetrafluoroethylene vascular prostheses. Methods: Since 1995, 14 patients with coronary …

OBJECTIVE: Conventional harvesting of saphenous vein used for coronary artery bypass
surgery induces a vasospasm that is overcome by high-pressure distension. Saphenous …

Saphenous vein graft (SVG) disease after coronary artery bypass grafting (CABG) occurs in
three phases: thrombosis, intimal hyperplasia, and atherosclerosis. Within the first month …

Perivascular adipose tissue (PVAT) releases numerous factors and adipokines with
paracrine effects on both vascular structure and function. These effects are variable as they …