Nucleic acids have been among the first targets for antitumor drugs and antibiotics. With the
unveiling of new biological roles in regulation of gene expression, specific DNA and RNA …

Nitrogen bases containing one or more pushing amino-group (s) directly linked to a pulling
cyano, imino, or phosphoimino group, as well as those in which the pushing and pulling …

Infrared multiphoton dissociation (IRMPD) spectroscopy is commonly used to determine the
structure of isolated, mass‐selected ions in the gas phase. This method has been widely …

Infrared multiple photon dissociation (IRMPD) spectroscopy is a powerful tool used to probe
the vibrational modes–and, by extension, the structure—of an ion within an ion trap mass …

The gas-phase conformations of protonated uridine,[Urd+ H]+, and its modified form,
protonated 2′-deoxyuridine,[dUrd+ H]+, generated by electrospray ionization are …

2′-Deoxyguanosine (dGuo) and guanosine (Guo) are fundamental building blocks of DNA
and RNA nucleic acids. In order to understand the effects of sodium cationization on the gas …

The influence of noncovalent interactions with a sodium cation on the gas-phase structures
and N-glycosidic bond stabilities of 2′-deoxyadenosine (dAdo) and adenosine …

Thymidine (dThd) is a fundamental building block of DNA nucleic acids, whereas 5-
methyluridine (Thd) is a common modified nucleoside found in tRNA. In order to determine …

Uridine (Urd) is one of the naturally occurring pyrimidine nucleosides of RNA. 2′-
Deoxyuridine (dUrd) is a naturally occurring modified form of Urd, but is not one of the …

IRMPD action spectroscopy studies of protonated 2′-deoxycytidine and cytidine,[dCyd+
H]+ and [Cyd+ H]+, have established that both N3 and O2 protonated conformers coexist in …