HIV-1 diversity and pre-treatment drug resistance in the era of integrase inhibitor among newly diagnosed ART-naïve adult patients in Luanda, Angola

CS Sebastião, AB Abecasis, D Jandondo… - Scientific Reports, 2024 - nature.com
The surveillance of drug resistance in the HIV-1 naïve population remains critical to
optimizing the effectiveness of antiretroviral therapy (ART), mainly in the era of integrase …

[HTML][HTML] Increased prevalence of pretreatment drug resistance mutations in treatment-naïve people living with HIV-1 in Henan Province, China (2022/23)

J Liu, C Liu, Y Wang, S Wei, J Ma, Y Li, X Chen… - Infection, Genetics and …, 2023 - Elsevier
Human deficiency virus type 1 (HIV-1) harboring drug resistance mutations (DRMs) before
the initiation of antiretroviral therapy (ART) poses a serious threat to the efficacy of current …

HIV-1 Low-Frequency Variants Identified in Antiretroviral-Naïve Subjects with Virologic Failure after 12 Months of Follow-Up in Panama

A Moreno, C González, J Góndola, O Chavarría… - Infectious Disease …, 2023 - mdpi.com
Low-frequency mutations associated with drug resistance have been related to virologic
failure in subjects with no history of pre-treatment and recent HIV diagnosis. In total, 78 …

Preliminary report of transmitted drug resistance to integrase strand chain transfer inhibitors in treatment-naïve HIV infected patients

P Ferrer, V Ramos, MI Puente, A Afani - Diagnostic Microbiology and …, 2023 - Elsevier
Transmitted Resistance exists in a newly diagnosed person who has not yet started their
treatment. Our objective was to obtain a profile of HIV-1 resistance to integrase inhibitors in …