This review summarizes the changes in the 5th edition of the WHO Classification of
Endocrine and Neuroendocrine Tumors that relate to the thyroid gland. The new …

The molecular characterization of poorly and anaplastic thyroid carcinomas has been
greatly improved in the last years following the advent of high throughput technologies …

Background: Anaplastic thyroid carcinoma (ATC) is nearly always fatal. Large studies on
ATC are exceedingly rare. We aimed to study the clinical, genotypic, and histologic …

Next generation sequencing (NGS) allows parallel sequencing of multiple genes at a very
high depth of coverage. The need to analyze a variety of targets for diagnostic/prognostic …

Background Anaplastic thyroid cancer (ATC) is a rare but lethal malignancy, and few
systematic investigations on genomic profiles of ATC have been performed in Chinese …

Abstract In the upcoming World Health Organization fifth edition classification of endocrine
tumors, there were several major changes related to high grade follicular-derived thyroid …

Background: Papillary thyroid cancers (PTCs) are common, usually indolent malignancies.
Still, a small but significant percentage of patients have aggressive tumors and develop …

Anaplastic carcinoma (AC) is a rare but highly aggressive form of thyroid cancer. It mostly
arises on a background of pre-existing well-differentiated cancer (WDC); however, whether it …

Anaplastic thyroid cancer (ATC) is a rare and extremely malignant tumor with no available
cure. The genetic landscape of this malignancy has not yet been fully explored. In this study …

Background: Distant metastasis is a rare occurrence in thyroid cancer, and it can be
associated with poor prognosis. The genomic repertoires of various solid malignancies have …