The role of mitochondrial function in health and disease has become increasingly
recognized, particularly in the last two decades. Mitochondrial dysfunction as well as …

Sphingolipids are a class of membrane lipids that serve as vital structural and signaling
bioactive molecules in organisms ranging from yeast to animals. Recent studies have …

Abstract Post-acute COVID-19 (PACS) are associated with cardiovascular dysfunction,
especially postural orthostatic tachycardia syndrome (POTS). Patients with PACS, both in …

Plasma lipid levels are altered in chronic conditions such as type 2 diabetes and
cardiovascular disease as well as during acute stresses such as fasting and cold exposure …

Background Skeletal muscle exhibits remarkable plasticity under both physiological and
pathological conditions. One major manifestation of this plasticity is muscle atrophy that is an …

Sphingolipids are a family of lipid molecules produced through different pathways in
mammals. Sphingolipids are structural components of membranes, but in response to …

Aims/hypothesis Energy-dense nutrition generally induces insulin resistance, but dietary
composition may differently affect glucose metabolism. This study investigated initial effects …

Biomarkers are important tools for describing the adequacy or inadequacy of biological
processes (to allow for the early and accurate diagnosis) and monitoring the biological …

Ceramides have been shown to play a major role in the onset of skeletal muscle insulin
resistance and therefore in the prevalence of type 2 diabetes. However, many of the studies …

Background: Efficient and controlled internalization of NPs into the cells depends on their
physicochemical properties and dynamics of the plasma membrane. NPs-cell interaction is a …