lncRNA involvement in cancer stem cell function and epithelial-mesenchymal transitions

EM McCabe, TP Rasmussen - Seminars in cancer biology, 2021 - Elsevier
Epithelial to mesenchymal transition (EMT) is a cellular process in which cells composing
epithelial tissue lose requirements for physical contact with neighboring cells and acquire …

[HTML][HTML] Biological functions and clinical significance of long noncoding RNAs in bladder cancer

Y Zhang, X Chen, J Lin, X Jin - Cell death discovery, 2021 - nature.com
Bladder cancer (BCa) is one of the 10 most common cancers with high morbidity and
mortality worldwide. Long noncoding RNAs (lncRNAs), a large class of noncoding RNA …

[HTML][HTML] LncRNA LINC00460 promotes EMT in head and neck squamous cell carcinoma by facilitating peroxiredoxin-1 into the nucleus

Y Jiang, W Cao, K Wu, X Qin, X Wang, Y Li… - Journal of Experimental …, 2019 - Springer
Abstract Background The lncRNA LINC00460 plays crucial roles in several epithelial
cancers, although its mechanisms of action differ greatly in different cellular contexts. In this …

LncRNA LINC00665 promotes prostate cancer progression via miR-1224-5p/SND1 axis

W Chen, Z Yu, W Huang, Y Yang, F Wang… - OncoTargets and …, 2020 - Taylor & Francis
Background Increasing researches have revealed a critical role of long noncoding RNAs
(lncRNAs) in tumor progression. LINC00665 is a poorly investigated lncRNA. In this …

Long noncoding RNA SNHG12 indicates the prognosis of prostate cancer and accelerates tumorigenesis via sponging miR‐133b

G Cheng, Z Song, Y Liu, H Xiao, H Ruan… - Journal of cellular …, 2020 - Wiley Online Library
Prostate cancer (PCa) is the second leading cause of death among American men.
Increasing evidence has shown that long noncoding RNAs (lncRNAs) play important roles in …

[HTML][HTML] Down-regulation of FTO promotes proliferation and migration, and protects bladder cancer cells from cisplatin-induced cytotoxicity

L Wen, X Pan, Y Yu, B Yang - BMC urology, 2020 - Springer
Background FTO is known to be associated with body mass and obesity in humans and its
over-expression affects the energy metabolism of cancer cells. The aim of the present study …

[HTML][HTML] Identification of a prognostic model based on fatty acid metabolism-related genes of head and neck squamous cell carcinoma

P Du, Y Chai, S Zong, J Yue, H Xiao - Frontiers in Genetics, 2022 - frontiersin.org
The fatty acid metabolism (FAM) is known to impact tumorigenesis, tumor progression and
treatment resistance via enhancing lipid synthesis, storage and catabolism. However, the …

[HTML][HTML] Long non-coding RNA LINC00460 promotes head and neck squamous cell carcinoma cell progression by sponging miR-612 to up-regulate AKT2

X Xie, G Xiong, Q Wang, Y Ge, X Cui - American journal of …, 2019 - ncbi.nlm.nih.gov
LncRNAs (long noncoding RNAs) have been shown to be potentially critical regulators in
head and neck squamous cell carcinoma (HNSCC). LncRNA LINC00460 (long intergenic …

[HTML][HTML] Endocrine nuclear receptors and long non-coding RNAs reciprocal regulation in cancer

M Cantile, M Cerrone, M Di Bonito… - International …, 2023 - spandidos-publications.com
Nuclear receptors (NRs) are transcriptional regulators involved in different aspects of normal
cell physiology. Their deregulation is associated with aberrant expression, gene mutations …

[HTML][HTML] Interaction between non-coding RNAs and androgen receptor with an especial focus on prostate cancer

M Taheri, T Khoshbakht, E Jamali, J Kallenbach… - Cells, 2021 - mdpi.com
The androgen receptor (AR) is a member of the nuclear receptor superfamily and has three
functional domains, namely the N-terminal, DNA binding, and C-terminal domain. The N …