One of the most critical epigenetic signatures present in the genome of higher eukaryotes is
the methylation of DNA at the C-5 position of the cytosine ring. Based on the sites of DNA …

The diagnosis of neurodegenerative disorders is often challenging due to the lack of
diagnostic tools, comorbidities and shared pathological manifestations. Synaptic dysfunction …

Background Synaptic dysfunction and degeneration are central contributors to the
pathogenesis and progression of parkinsonian disorders. Therefore, identification and …

Parkinson's disease (PD) is a prevalent neurodegenerative aging disorder that manifests as
motor and non-motor symptoms, and its etiopathogenesis is influenced by non-coding RNAs …

According to current paradigms, various risk factors, such as genetic mutations, oxidative
stress, neural network dysfunction, and abnormal protein degradation, contribute to the …

Alzheimer's disease (AD), Parkinson's disease (PD), and Amyotrophic Lateral Sclerosis
(ALS) are representative neurodegenerative diseases (NDs) characterized by degeneration …

Aging-related neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's
disease (PD), Huntington's disease (HD), and amyotrophic lateral sclerosis (ALS), are …

Parkinson's disease (PD) seriously threatens human's health. Researches have shown a
close correlation between long non-coding RNAs (lncRNAs) and PD. However, the …

Diabetic foot ulcer is a severe complication of diabetes and is prone to being a chronic non-
healing wound. We previously demonstrated that endothelial progenitor cell-derived …

MicroRNAs (miRNAs) are critical regulators of gene expression in healthy and diseased
states, and numerous studies have established their tremendous potential as a tool for …