STAT proteins: a kaleidoscope of canonical and non-canonical functions in immunity and cancer

N Awasthi, C Liongue, AC Ward - Journal of hematology & oncology, 2021 - Springer
STAT proteins represent an important family of evolutionarily conserved transcription factors
that play key roles in diverse biological processes, notably including blood and immune cell …

Differentiating between UCTD and early-stage SLE: from definitions to clinical approach

S Sciascia, D Roccatello, M Radin, I Parodis… - Nature Reviews …, 2022 - nature.com
Systemic lupus erythematosus (SLE) is an autoimmune disease with heterogeneous clinical
manifestations that can potentially affect every organ and system. SLE is usually identified …

Combined proteomics and single cell RNA-sequencing analysis to identify biomarkers of disease diagnosis and disease exacerbation for systemic lupus …

Y Li, C Ma, S Liao, S Qi, S Meng, W Cai, W Dai… - Frontiers in …, 2022 - frontiersin.org
Introduction Systemic lupus erythematosus (SLE) is a chronic autoimmune disease for which
there is no cure. Effective diagnosis and precise assessment of disease exacerbation …

[HTML][HTML] SARS-Cov2 acute and post-active infection in the context of autoimmune and chronic inflammatory diseases

R Larionova, K Byvaltsev, О Kravtsova, E Takha… - Journal of Translational …, 2022 - Elsevier
The clinical and immunological spectrum of acute and post-active COVID-19 syndrome
overlaps with criteria used to characterize autoimmune diseases such as rheumatoid …

Identification of key interferon-stimulated genes for indicating the condition of patients with systemic lupus erythematosus

M Shen, C Duan, C Xie, H Wang, Z Li, B Li… - Frontiers in …, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with highly
heterogeneous clinical symptoms and severity. There is complex pathogenesis of SLE, one …

Placental damage in pregnancies with systemic lupus erythematosus: A narrative review

AS Castellanos Gutierrez, F Figueras… - Frontiers in …, 2022 - frontiersin.org
Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease of
unknown cause, which mainly affects women of childbearing age, especially between 15 …

The crucial regulatory role of type I interferon in inflammatory diseases

L Ji, T Li, H Chen, Y Yang, E Lu, J Liu, W Qiao, H Chen - Cell & Bioscience, 2023 - Springer
Abstract Type I interferon (IFN-I) plays crucial roles in the regulation of inflammation and it is
associated with various inflammatory diseases including systemic lupus erythematosus …

Interferons and systemic lupus erythematosus: Pathogenesis, clinical features, and treatments in interferon-driven disease

Y Tanaka, M Kusuda, Y Yamaguchi - Modern Rheumatology, 2023 - academic.oup.com
Type I interferons (IFNs) have recently received a lot of attention with the elucidation of the
pathogenesis of systemic lupus erythematosus (SLE). Type I IFNs are associated with many …

Novel heterozygous TREX1 mutation in a juvenile systemic lupus erythematosus patient with severe cutaneous involvement treated successfully with Jak-inhibitors: a …

M Rossano, EA Conti, P Bocca, S Volpi… - Frontiers in …, 2023 - frontiersin.org
Juvenile systemic lupus erythematosus (jSLE) is a complex inflammatory autoimmune
disorder. In the last decades, genetic factors and activation pathways have been …

Gene signature of regulatory T Cells isolated from children with selective IgA deficiency and common variable immunodeficiency

M Rutkowska-Zapała, A Grabowska-Gurgul, M Lenart… - Cells, 2024 - mdpi.com
Selective IgA deficiency (SIgAD) is the most common form and common variable
immunodeficiency (CVID) is the most symptomatic form of predominant antibody deficiency …