Progress in and promise of bacterial quorum sensing research
This Review highlights how we can build upon the relatively new and rapidly developing
field of research into bacterial quorum sensing (QS). We now have a depth of knowledge …
field of research into bacterial quorum sensing (QS). We now have a depth of knowledge …
Quorum-sensing systems as targets for antivirulence therapy
T Defoirdt - Trends in microbiology, 2018 - cell.com
The development of novel therapies to control diseases caused by antibiotic-resistant
pathogens is one of the major challenges we are currently facing. Many important plant …
pathogens is one of the major challenges we are currently facing. Many important plant …
Pseudomonas aeruginosa Biofilms: Host Response and Clinical Implications in Lung Infections
NM Maurice, B Bedi, RT Sadikot - American journal of respiratory …, 2018 - atsjournals.org
Pseudomonas aeruginosa is a major health challenge that causes recalcitrant multidrug-
resistant infections, especially in immunocompromised and hospitalized patients. P …
resistant infections, especially in immunocompromised and hospitalized patients. P …
Bacterial quorum sensing during infection
S Azimi, AD Klementiev, M Whiteley… - Annual review of …, 2020 - annualreviews.org
Bacteria are highly interactive and possess an extraordinary repertoire of intercellular
communication and social behaviors, including quorum sensing (QS). QS has been studied …
communication and social behaviors, including quorum sensing (QS). QS has been studied …
Evolution of the Pseudomonas aeruginosa quorum-sensing hierarchy
The bacterial pathogen Pseudomonas aeruginosa activates expression of many virulence
genes in a cell density-dependent manner by using an intricate quorum-sensing (QS) …
genes in a cell density-dependent manner by using an intricate quorum-sensing (QS) …
Natural quorum sensing inhibitors effectively downregulate gene expression of Pseudomonas aeruginosa virulence factors
At present, anti-virulence drugs are being considered as potential therapeutic alternatives
and/or adjuvants to currently failing antibiotics. These drugs do not kill bacteria but inhibit …
and/or adjuvants to currently failing antibiotics. These drugs do not kill bacteria but inhibit …
Molecular mechanisms and applications of N-acyl homoserine lactone-mediated quorum sensing in bacteria
Microbial biodiversity includes biotic and abiotic components that support all life forms by
adapting to environmental conditions. Climate change, pollution, human activity, and natural …
adapting to environmental conditions. Climate change, pollution, human activity, and natural …
Evolution of lasR mutants in polymorphic Pseudomonas aeruginosa populations facilitates chronic infection of the lung
K Zhao, X Yang, Q Zeng, Y Zhang, H Li, C Yan… - Nature …, 2023 - nature.com
Chronic infection with the bacterial pathogen Pseudomonas aeruginosa often leads to
coexistence of heterogeneous populations carrying diverse mutations. In particular, loss-of …
coexistence of heterogeneous populations carrying diverse mutations. In particular, loss-of …
The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone …
S Mukherjee, D Moustafa, CD Smith… - PLoS …, 2017 - journals.plos.org
Quorum sensing (QS) is a bacterial cell-to-cell communication process that relies on the
production, release, and response to extracellular signaling molecules called autoinducers …
production, release, and response to extracellular signaling molecules called autoinducers …
How Bacterial Adaptation to Cystic Fibrosis Environment Shapes Interactions Between Pseudomonas aeruginosa and Staphylococcus aureus
L Camus, P Briaud, F Vandenesch… - Frontiers in …, 2021 - frontiersin.org
Pseudomonas aeruginosa and Staphylococcus aureus are the two most prevalent bacteria
species in the lungs of cystic fibrosis (CF) patients and are associated with poor clinical …
species in the lungs of cystic fibrosis (CF) patients and are associated with poor clinical …