The dynamics of the skin's immune system

AV Nguyen, AM Soulika - International journal of molecular sciences, 2019 - mdpi.com
The skin is a complex organ that has devised numerous strategies, such as physical,
chemical, and microbiological barriers, to protect the host from external insults. In addition …

Endothelial tight junctions and their regulatory signaling pathways in vascular homeostasis and disease

X Cong, W Kong - Cellular signalling, 2020 - Elsevier
Endothelial tight junctions (TJs) regulate the transport of water, ions, and molecules through
the paracellular pathway, serving as an important barrier in blood vessels and maintaining …

Bioelectric signaling: role of bioelectricity in directional cell migration in wound healing

M Zhao, M Rolandi, RR Isseroff - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
In wound healing, individual cells' behaviors coordinate movement toward the wound center
to restore small or large barrier defects. The migration of epithelial cells as a continuous …

Dental pulp stem cells for bone tissue engineering: a literature review

X Bai, R Cao, D Wu, H Zhang, F Yang… - Stem Cells …, 2023 - Wiley Online Library
Bone tissue engineering (BTE) is a promising approach for repairing and regenerating
damaged bone tissue, using stem cells and scaffold structures. Among various stem cell …

[HTML][HTML] 3D-printed dermis-specific extracellular matrix mitigates scar contraction via inducing early angiogenesis and macrophage M2 polarization

L Chen, Z Li, Y Zheng, F Zhou, J Zhao, Q Zhai… - Bioactive materials, 2022 - Elsevier
Scar contraction frequently happens in patients with deep burn injuries. Hitherto, porcine
dermal extracellular matrix (dECM) has supplied microenvironments that assist in wound …

Ferroptosis in brain microvascular endothelial cells mediates blood-brain barrier disruption after traumatic brain injury

J Fang, Q Yuan, Z Du, M Fei, Q Zhang, L Yang… - Biochemical and …, 2022 - Elsevier
Ferroptosis is a newly recognized form of regulated cell death. Recently, growing evidence
has shown that ferroptosis is involved in the pathogenesis of traumatic brain injury (TBI) …

Lipid-based nanocarriers challenging the ocular biological barriers: Current paradigm and future perspectives

KK Abla, MM Mehanna - Journal of Controlled Release, 2023 - Elsevier
Eye is the most specialized and sensory body organ and treating eye diseases efficiently is
necessary. Despite various attempts, the design of a consummate ophthalmic drug delivery …

Current Status of In vitro Models of the Blood-brain Barrier

B Shah, X Dong - Current drug delivery, 2022 - benthamdirect.com
Disorders of the brain constitute the most debilitating situation globally with increased
mortality rates every year, while brain physiology and cumbersome drug development …

Recent advances in nanotechnology for Intra-nasal drug delivery and clinical applications

G Rai, P Gauba, S Dang - Journal of Drug Delivery Science and …, 2023 - Elsevier
Nanotechnology has proved its tremendous worth in the field of drug delivery and targeting.
Nano formulations have improved the safety and efficacy of various conventional drugs …

Rifampicin-Loaded Alginate-Gelatin Fibers Incorporated within Transdermal Films as a Fiber-in-Film System for Wound Healing Applications

A Sharma, V Puri, P Kumar, I Singh - Membranes, 2020 - mdpi.com
The various biological and molecular cascades including different stages or phases such as
inflammation, tissue proliferation, and remodeling phases, which significantly define the …