Artemisinin‐based combination therapy for treating uncomplicated malaria

D Sinclair, B Zani, S Donegan… - Cochrane Database …, 2009 - cochranelibrary.com
Background The World Health Organization recommends uncomplicated P. falciparum
malaria is treated using Artemisinin‐based Combination Therapy (ACT). This review aims to …

Malaria chemotherapeutics part I: History of antimalarial drug development, currently used therapeutics, and drugs in clinical development

M Schlitzer - ChemMedChem: Chemistry Enabling Drug …, 2007 - Wiley Online Library
Since ancient times, humankind has had to struggle against the persistent onslaught of
pathogenic microorganisms. Nowadays, malaria is still the most important infectious disease …

[HTML][HTML] From innovation to application: Social–ecological context, diagnostics, drugs and integrated control of schistosomiasis

J Utzinger, EK N'Goran, CR Caffrey, J Keiser - Acta tropica, 2011 - Elsevier
Compared to malaria, tuberculosis and HIV/AIDS, schistosomiasis remains a truly neglected
tropical disease. Schistosomiasis, perhaps more than any other disease, is entrenched in …

Current scenario of artemisinin and its analogues for antimalarial activity

A Kumari, M Karnatak, D Singh, R Shankar… - European journal of …, 2019 - Elsevier
Human malaria, one of the most striking, reemerging infectious diseases, is caused by
several types of Plasmodium parasites. Whilst advances have been made in lowering the …

Antimalarial actions of Lawsonia inermis, Tithonia diversifolia and Chromolaena odorata in combination

FID Afolayan, OM Adegbolagun, B Irungu… - Journal of …, 2016 - Elsevier
Abstract Ethnopharmacological relevance Chromolaena odorata, Tithonia diversifolia and
Lawsonia inermis are medicinal plants used in treating malaria in traditional medicine …

[HTML][HTML] Stimulation of suicidal erythrocyte death by the antimalarial drug mefloquine

R Bissinger, S Barking, K Alzoubi, G Liu… - Cellular Physiology and …, 2015 - karger.com
Background: The antimalarial drug mefloquine has previously been shown to stimulate
apoptosis of nucleated cells. Similar to apoptosis, erythrocytes may enter suicidal death or …

Are national treatment guidelines for falciparum malaria in line with WHO recommendations and is antimalarial resistance taken into consideration?–A review of …

MT Visser, R Zonneveld, TJ Peto… - Tropical Medicine & …, 2022 - Wiley Online Library
Objective Plasmodium falciparum infections are a relatively rare but potentially deadly
disease found in returning travellers. We compare the national treatment guidelines of non …

Pharmacokinetics of co-formulated mefloquine and artesunate in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum infection in Burkina …

I Valea, H Tinto, M Traore/Coulibaly… - Journal of …, 2014 - academic.oup.com
Objectives Mefloquine/artesunate has recently been developed as a fixed-dose
combination, providing a promising rescue/alternative treatment for malaria during …

Existing antimalarial agents and malaria-treatment strategies

U D'Alessandro - Expert opinion on pharmacotherapy, 2009 - Taylor & Francis
In the absence of prompt and efficacious treatment, malaria patients may progress within a
few hours from having minor symptoms to severe disease and death. These last years have …

Diagnosis and management of malaria in the intensive care unit

G Akafity, N Kumi, J Ashong - Journal of Intensive Medicine, 2024 - mednexus.org
Malaria is responsible for approximately three-quarters of a million deaths in humans
globally each year. Most of the morbidity and mortality reported are from Sub-Saharan Africa …