Fractionating impulsivity: neuropsychiatric implications
JW Dalley, TW Robbins - Nature Reviews Neuroscience, 2017 - nature.com
The ability to make decisions and act quickly without hesitation can be advantageous in
many settings. However, when persistently expressed, impulsive decisions and actions are …
many settings. However, when persistently expressed, impulsive decisions and actions are …
[PDF][PDF] The molecular basis of drug addiction: linking epigenetic to synaptic and circuit mechanisms
EJ Nestler, C Lüscher - Neuron, 2019 - cell.com
Addiction is a disease in which, after a period of recreational use, a subset of individuals
develops compulsive use that does not stop even in light of major negative consequences …
develops compulsive use that does not stop even in light of major negative consequences …
Better living through understanding the insula: Why subregions can make all the difference
Insula function is considered critical for many motivated behaviors, with proposed functions
ranging from attention, behavioral control, emotional regulation, goal-directed and aversion …
ranging from attention, behavioral control, emotional regulation, goal-directed and aversion …
[HTML][HTML] Bi-directional regulation of cognitive control by distinct prefrontal cortical output neurons to thalamus and striatum
SF de Kloet, B Bruinsma, H Terra, TS Heistek… - Nature …, 2021 - nature.com
The medial prefrontal cortex (mPFC) steers goal-directed actions and withholds
inappropriate behavior. Dorsal and ventral mPFC (dmPFC/vmPFC) circuits have distinct …
inappropriate behavior. Dorsal and ventral mPFC (dmPFC/vmPFC) circuits have distinct …
Meta-analyses of the functional neural alterations in subjects with Internet gaming disorder: Similarities and differences across different paradigms
Internet gaming disorder (IGD) has become a global public health concern due to its
increasing prevalence and potential negative consequences. Researchers have sought to …
increasing prevalence and potential negative consequences. Researchers have sought to …
[HTML][HTML] Neuromodulation of OCD: A review of invasive and non-invasive methods
Early research into neural correlates of obsessive compulsive disorder (OCD) has focused
on individual components, several network-based models have emerged from more recent …
on individual components, several network-based models have emerged from more recent …
From compulsivity to compulsion: the neural basis of compulsive disorders
Compulsive behaviour, an apparently irrational perseveration in often maladaptive acts, is a
potential transdiagnostic symptom of several neuropsychiatric disorders, including …
potential transdiagnostic symptom of several neuropsychiatric disorders, including …
Neural correlates of compulsive alcohol seeking in heavy drinkers
Background Compulsive alcohol use, the tendency to continue alcohol seeking and taking
despite negative consequences, is a hallmark of alcohol use disorder. Preclinical rodent …
despite negative consequences, is a hallmark of alcohol use disorder. Preclinical rodent …
Deep brain stimulation modulates directional limbic connectivity in obsessive-compulsive disorder
Deep brain stimulation is effective for patients with treatment-refractory obsessive-
compulsive disorder. Deep brain stimulation of the ventral anterior limb of the internal …
compulsive disorder. Deep brain stimulation of the ventral anterior limb of the internal …
Structural deficits in salience network regions are associated with increased impulsivity and compulsivity in alcohol dependence
EN Grodin, CR Cortes, PA Spagnolo… - Drug and alcohol …, 2017 - Elsevier
Background Convergent preclinical and clinical evidence has linked the anterior insula to
impulsivity and alcohol-associated compulsivity. The anterior insula is functionally …
impulsivity and alcohol-associated compulsivity. The anterior insula is functionally …