Mesenchymal stem cell derived extracellular vesicles for tissue engineering and regenerative medicine applications
D Tsiapalis, L O'Driscoll - Cells, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) are being extensively investigated for their potential in
tissue engineering and regenerative medicine. However, recent evidence suggests that the …
tissue engineering and regenerative medicine. However, recent evidence suggests that the …
[HTML][HTML] Extracellular vesicles as bioactive nanotherapeutics: an emerging paradigm for regenerative medicine
In recent decades, extracellular vesicles (EVs), as bioactive cell-secreted nanoparticles
which are involved in various physiological and pathological processes including cell …
which are involved in various physiological and pathological processes including cell …
Differential therapeutic effect of extracellular vesicles derived by bone marrow and adipose mesenchymal stem cells on wound healing of diabetic ulcers and …
Extracellular vesicles (EVs) derived from mesenchymal stem cells isolated from both bone
marrow (BMSCs) and adipose tissue (ADSCs) show potential therapeutic effects. These …
marrow (BMSCs) and adipose tissue (ADSCs) show potential therapeutic effects. These …
Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes
C Zheng, B Sui, X Zhang, J Hu, J Chen… - Journal of …, 2021 - Wiley Online Library
Apoptosis is a naturally occurring process generating plenty of apoptotic vesicles (apoVs),
but the feature, fate and function of apoVs remain largely unknown. Notably, as an …
but the feature, fate and function of apoVs remain largely unknown. Notably, as an …
Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities
A Nagelkerke, M Ojansivu, L van der Koog… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting
as delivery vehicles for molecular messages. During the last decade, EVs have been …
as delivery vehicles for molecular messages. During the last decade, EVs have been …
Adipose‐derived mesenchymal stem cell‐derived exosomes biopotentiated extracellular matrix hydrogels accelerate diabetic wound healing and skin regeneration
Y Song, Y You, X Xu, J Lu, X Huang, J Zhang… - Advanced …, 2023 - Wiley Online Library
Wound healing is an urgent clinical challenge, particularly in the case of chronic wounds.
Traditional approaches to wound healing have limited therapeutic efficacy due to lengthy …
Traditional approaches to wound healing have limited therapeutic efficacy due to lengthy …
[HTML][HTML] Extracellular vesicle-based Nanotherapeutics: Emerging frontiers in anti-inflammatory therapy
TT Tang, B Wang, LL Lv, BC Liu - Theranostics, 2020 - ncbi.nlm.nih.gov
Dysregulated inflammation is a complicated pathological process involved in various
diseases, and the treatment of inflammation-linked disorders currently represents an …
diseases, and the treatment of inflammation-linked disorders currently represents an …
Mesenchymal stem cell-derived extracellular vesicles: regenerative potential and challenges
Simple Summary Mesenchymal stem cell extracellular vesicles (MSCEVs) obtained from
MSCs can have numerous therapeutic applications via regeneration of various body tissues …
MSCs can have numerous therapeutic applications via regeneration of various body tissues …
[HTML][HTML] Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair
Although stem cell-derived extracellular vesicles (EVs) have remarkable therapeutic
potential for various diseases, the therapeutic efficacy of EVs is limited due to their …
potential for various diseases, the therapeutic efficacy of EVs is limited due to their …
Exosomes derived from adipose-derived stem cells overexpressing glyoxalase-1 protect endothelial cells and enhance angiogenesis in type 2 diabetic mice with limb …
X Zhang, Y Jiang, Q Huang, Z Wu, H Pu, Z Xu… - Stem Cell Research & …, 2021 - Springer
Background Diabetic limb ischemia is a clinical syndrome and refractory to therapy. Our
previous study demonstrated that adipose-derived stem cells (ADSCs) overexpressing …
previous study demonstrated that adipose-derived stem cells (ADSCs) overexpressing …