Long-term and sequential treatment for osteoporosis

I Foessl, HP Dimai, B Obermayer-Pietsch - Nature Reviews …, 2023 - nature.com
Osteoporosis is a skeletal disorder that causes impairment of bone structure and strength,
leading to a progressively increased risk of fragility fractures. The global prevalence of …

Insights and implications of sexual dimorphism in osteoporosis

YY Zhang, N Xie, XD Sun, EC Nice, YC Liou, C Huang… - Bone research, 2024 - nature.com
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

In Vitro Evaluation of Ag- and Sr-Doped Hydroxyapatite Coatings for Medical Applications

E Ungureanu, A Vladescu, AC Parau, V Mitran… - Materials, 2023 - mdpi.com
Osseointegration plays the most important role in the success of an implant. One of the
applications of hydroxyapatite (HAp) is as a coating for metallic implants due to its bioactive …

Impact of nanoparticle physicochemical properties on protein corona and macrophage polarization

B Xiao, Y Liu, I Chandrasiri, C Overby… - ACS Applied Materials …, 2023 - ACS Publications
Macrophages, the major component of the mononuclear phagocyte system, uptake and
clear systemically administered nanoparticles (NPs). Therefore, leveraging macrophages as …

Lactobacillus acidophilus (LA) Fermenting Astragalus Polysaccharides (APS) Improves Calcium Absorption and Osteoporosis by Altering Gut Microbiota

J Zhou, J Cheng, L Liu, J Luo, X Peng - Foods, 2023 - mdpi.com
Lactobacillus acidophilus (LA) and Astragalus polysaccharides (APS) have each been
shown to have anti-osteoporotic activity, and the aim of this study was to further investigate …

Bone‐Targeted Nanoparticle Drug Delivery System‐Mediated Macrophage Modulation for Enhanced Fracture Healing

B Xiao, Y Liu, I Chandrasiri, E Adjei‐Sowah… - Small, 2024 - Wiley Online Library
Despite decades of progress, developing minimally invasive bone‐specific drug delivery
systems (DDS) to improve fracture healing remains a significant clinical challenge. To …

Radiofrequency Echographic Multispectrometry (REMS) can overcome the effects of Structural Internal artifacts and evaluate bone fragility accurately

H Ishizu, T Shimizu, Y Sakamoto, F Toyama… - Calcified Tissue …, 2024 - Springer
Purpose This study measured bone mineral density (BMD) in a Japanese population using
the novel non-ionizing system using radiofrequency echographic multispectrometry (REMS) …

Osteoporosis, osteoarthritis, and subchondral insufficiency fracture: recent insights

S Yokota, H Ishizu, T Miyazaki, D Takahashi, N Iwasaki… - Biomedicines, 2024 - mdpi.com
The increased incidence of osteoarthritis (OA), particularly knee and hip OA, and
osteoporosis (OP), owing to population aging, have escalated the medical expense burden …

The Dietary and Non-Dietary Management of Osteoporosis in Adult-Onset Celiac Disease: Current Status and Practical Guidance

A Al-Toma, A Herman, WF Lems, CJJ Mulder - Nutrients, 2022 - mdpi.com
Impaired bone mineral density (BMD) is a frequent complication of adult-onset celiac
disease (CeD). This is usually due to malabsorption of nutrients, changes in bone …

Assessment of spatially offset Raman spectroscopy to detect differences in bone matrix quality

R Gautam, R Ahmed, E Haugen, M Unal… - … Acta Part A: Molecular …, 2023 - Elsevier
Since spatially offset Raman spectroscopy (SORS) can acquire biochemical measurements
of tissue quality through light scattering materials, we investigated the feasibility of this …