Pulmonary studies using positron emission tomography

CG Rhodes, JM Hughes - European Respiratory Journal, 1995 - Eur Respiratory Soc
The detailed investigation of regional differences in lung function at a local level began
when suitable gamma-ray emitting isotopes and focused external radiation detectors …

Noninvasive Measurement of mTORC1 Signaling with 89Zr-Transferrin

C Truillet, JT Cunningham, MFL Parker, LT Huynh… - Clinical Cancer …, 2017 - AACR
Purpose: mTOR regulates many normal physiological processes and when hyperactive can
drive numerous cancers and human diseases. However, it is very challenging to detect and …

The evaluation of lung function with PET

DP Schuster - Seminars in nuclear medicine, 1998 - Elsevier
In many ways, the lung is an ideal organ for study with positron emission tomography (PET).
First, structure-function relations are homogeneous over larger areas than in other organs …

Past and future of Ga-citrate for infection and inflammation imaging

M Vorster, J Buscombe, Z Saad… - Current Pharmaceutical …, 2018 - ingentaconnect.com
Both 67Ga and 68Ga-citrates are used to detect a wide spectrum of pathology consisting of
various inflammatory, infectious and malignant conditions. Considering the now widespread …

Acute lung injury and pulmonary vascular permeability: use of transgenic models

JC Parker - Comprehensive Physiology, 2011 - Wiley Online Library
Acute lung injury is a general term that describes injurious conditions that can range from
mild interstitial edema to massive inflammatory tissue destruction. This review will cover …

Synthesis and biodistribution of lipophilic and monocationic gallium radiopharmaceuticals derived from N, N′-bis (3-aminopropyl)-N, N′-dimethylethylenediamine …

YM Hsiao, CJ Mathias, SP Wey, PE Fanwick… - Nuclear medicine and …, 2009 - Elsevier
INTRODUCTION: In locations that lack nearby cyclotron facilities for radionuclide production,
generator-based 68Ga radiopharmaceuticals might have clinical utility for positron emission …

Clinical molecular imaging with radiotracers: current status

MM Graham - Medical Principles and Practice, 2012 - karger.com
Molecular imaging is defined as the visualization, characterization, and measurement of
biological processes at the molecular and cellular levels in humans and other living …

Utilization of metabolic, transport and receptor-mediated processes to deliver agents for cancer diagnosis

CS Cutler, JS Lewis, CJ Anderson - Advanced drug delivery reviews, 1999 - Elsevier
The use of radiopharmaceuticals for the non-invasive diagnosis of cancer has been
established in diagnostic radiology over the last few decades. In particular, with the use of …

[PDF][PDF] A new myocardial imaging agent: synthesis, characterization, and biodistribution of gallium-68-BAT-TECH

HF Kung, BL Liu, D Mankoff, MP Kung… - Journal of Nuclear …, 1990 - Soc Nuclear Med
No-carrier-added 67Ga-citrate (1 mCi/ml) was added to a test tube containing the BAT-
TECH ligand (1 mg) in 0.5 ml of water and adjusting the pH to 3.1 ±0.1 by the dropwise …

Gallium-68: a systematic review of its nononcological applications

M Vorster, A Maes, C Van deWiele… - Nuclear Medicine …, 2013 - journals.lww.com
The increased availability of PET facilities worldwide has sparked renewed interest in the
use of generator-produced tracers such as gallium-68 (68 Ga). Imaging with 68 Ga provides …