[HTML][HTML] HIV subtype diversity worldwide

N Bbosa, P Kaleebu, D Ssemwanga - Current Opinion in HIV and …, 2019 - journals.lww.com
The dynamic change in HIV subtype distribution presents future challenges for diagnosis,
treatment and vaccine design and development. An increase in recombinant viruses …

Rising role of 3D-printing in delivery of therapeutics for infectious disease

AJ Kyser, B Fotouh, MY Mahmoud… - Journal of Controlled …, 2024 - Elsevier
Modern drug delivery to tackle infectious disease has drawn close to personalizing medicine
for specific patient populations. Challenges include antibiotic-resistant infections, healthcare …

[HTML][HTML] HIV-1 transmission patterns within and between risk groups in coastal Kenya

GM Nduva, AS Hassan, J Nazziwa, SM Graham… - Scientific reports, 2020 - nature.com
HIV-1 transmission patterns within and between populations at different risk of HIV-1
acquisition in Kenya are not well understood. We investigated HIV-1 transmission networks …

Quantifying rates of HIV-1 flow between risk groups and geographic locations in Kenya: A country-wide phylogenetic study

GM Nduva, F Otieno, J Kimani, E Wahome… - Virus …, 2022 - academic.oup.com
In Kenya, HIV-1 key populations including men having sex with men (MSM), people who
inject drugs (PWID) and female sex workers (FSW) are thought to significantly contribute to …

[HTML][HTML] HIV-1 subtype diversity, transmission networks and transmitted drug resistance amongst acute and early infected MSM populations from Coastal Kenya

AS Hassan, J Esbjörnsson, E Wahome, A Thiong'o… - PLoS …, 2018 - journals.plos.org
Background HIV-1 molecular epidemiology amongst men who have sex with men (MSM) in
sub-Saharan Africa remains not well characterized. We aimed to determine HIV-1 subtype …

[HTML][HTML] Prospective evaluation of accuracy of HIV viral load monitoring using the Aptima HIV Quant Dx assay with fingerstick and venous dried blood spots prepared …

M Mwau, J Danda, J Mbugua, A Handa, J Fortunko… - PLoS …, 2021 - journals.plos.org
Quantification of HIV-1 RNA is essential for clinical management of HIV patients. The limited
throughput and significant hands-on time required by most HIV Viral load (VL) tests makes it …

[HTML][HTML] Partial compartmentalisation of HIV-1 subtype C between lymph nodes, peripheral blood mononuclear cells and plasma

N Jeewanraj, T Mandizvo, T Mulaudzi, N Gumede… - Virology, 2023 - Elsevier
HIV-1 compartmentalisation is likely to have important implications for a preventative
vaccine as well as eradication strategies. We genetically characterised HIV-1 subtype C …

[HTML][HTML] Comparison of the performance of Aptima HIV-1 Quant Dx Assay with Abbott RealTime HIV Assay for viral load monitoring using plasma and Dried Blood …

M Mwau, S Schaffer, H Kimani, P Kasiano, F Ogolla… - Plos one, 2022 - journals.plos.org
Introduction HIV-1 viral Load (VL) testing is recommended for the monitoring of antiretroviral
treatment. Dried Blood Spots (DBS) are an effective sample type in resource limited settings …

HIV-1 Transmission Cluster in Injection Drug Users in Nairobi City, Kenya

SK Webale, M Kilongosi, G Munyekenye… - Ethiopian Journal of …, 2023 - ajol.info
BACKGROUND: While there is a striking increase in the prevalence of HIV in injection drug
users, information on envelope-gene subtypes and transmission clusters in injection drug …

[HTML][HTML] Human immunodeficiency virus type 1 (HIV-1) subtype diversity in Busia, Western Kenya

JM Kingoo, AWT Muigai, V Matiru… - African Journal of …, 2021 - academicjournals.org
ABSTRACT HIV infection is currently the single biggest epidemic globally. HIV the etiologic
agent for AIDS is divided into two types: HIV-1 and HIV-2. HIV-2 is rare and is mainly found …